Co-Founder and Chief Technology Officer, Oxford HighQ

Oxford HighQ is a spin-out company from the University of Oxford’s Departments of Materials and Chemistry. It is developing nanoparticle sensing instruments that are up to 10,000 times more sensitive than available optical sensing technologies. The company has engineered a way of producing large-scale, repeatable, high precision optical microcavities for the first time.

These sensors will enable new tools to be created in pharmaceutical and medical research, as well as food and water monitoring. This technology could prove a step-change in performance for chemical and nanoparticle sensing.

Aurélien Trichet is Co-Founder and CTO at Oxford HighQ, managing the R&D team and directing technology development. He became an SME Leader in 2020 and is looking forward to using the programme. He says: “This opportunity is ideal for me. It will allow me to move from a heavy academic skillset to a more business and technology management one. The workshop, coaching and mentoring will all help me make this transition.”

Oxford HighQ is aiming to transition from R&D to mass production in 2021. Its first product provides a way to measure drug loading and delivery profiles as well as particle size for nanomedicine applications. As a consequence, researchers within academic institutions, SMEs and pharmaceutical companies will have better quality assurance procedures, a crucial requirement in this valuable industry.

Research shows that 23% of the world’s energy is lost through tribological contact, which is the wear and friction generated by interacting surfaces in motion.

Tribosonics Limited, a Sheffield company, has developed sensing technology to tackle wear, friction and lubrication issues in rotating equipment. The business venture designs, manufactures and installs high-end, often bespoke, ultrasonic sensing and data capture platforms across many industrial sectors.

Tribosonics inserts sensors within bearings, seals and other moving parts to create smart components that can measure and monitor tribological contact as well as other performance and structural metrics.  The generated data helps companies to extend plant life, prevent critical failures, shorten maintenance cycles and reduce energy use through improved operational efficiency. 

Christina King is the Chief Commercial Officer for Tribosonics, responsible for building innovative commercial partnerships with large corporations. Christina joined the SME Leaders programme in 2021 and says “I want to gain business insights and build networks that will help develop my personal journey, as well as scale-up the company.”

In 2020, Tribosonics secured over £1 million of equity investment from the Northern Powerhouse Investment Fund, via Mercia Asset Management. This will enable the company to double in size over the next three years. It is now looking to further expand its patented ultrasonic sensing technologies into global industrial markets.

Lightpoint Medical develops molecular imaging and sensing technologies to help surgeons detect cancer in real time during surgery. In spite of the technological advances in robotic surgery, surgeons still depend on their eyesight to detect cancer intra-operatively. As a result, surgeons sometimes leave cancer behind or remove more healthy tissue than needed.

The company’s award-winning SENSEI® technology, a miniaturised intra-operative cancer detection probe, gives surgeons a chance to fully remove cancer in one procedure, while retaining healthy tissue. It can be used across many major cancer types including stomach, colorectal, breast, prostate, and lung cancer.

Dr Kunal Vyas is the Head of Research at Lightpoint Medical, responsible for evaluating new technologies, overseeing research projects and developing the company’s intellectual property (IP) portfolio. Kunal joined the SME Leaders programme in 2021. He says “I hope that the programme’s strategic innovation management initiative will maximise my performance as we commercialise and scale-up. I will also benefit from access to workshops and speaker events on topics such as IP management and pitching.”

In 2021, SENSEI® received CE mark, enabling it to be sold in the European Economic Area. Lightpoint Medical has begun multi-centre clinical trials with the probe. The company will now transition from being an R&D-focused organisation into a commercial enterprise.

The problem

Loudspeakers are used in billions of devices worldwide including smartphones, laptops, tablets and smart speakers. For nearly 100 years, the dominant technology to reproduce sound has been the dynamic loudspeaker. One of the main mechanisms it uses is the voice coil transducer, a very simple device that also has significant drawbacks in terms of electrics, mechanics and acoustics.

The solution

Dominika Behounik is Co-Founder and Chief Technical Officer of Arya Audio Labs. The company was formed with Arthur Marker to develop audio products. One of these was the AirBlade transducer. Instead of trying to incrementally improve a 100-year old imperfect design, it approached the problem from a different, disruptive angle.

Rather than using a heavy diaphragm with separate voice coil, the AirBlade transducer incorporates ultralight ring-shaped foil elements arranged in layers with conductive traces of aluminium bonded to it. When an electrical signal is applied, opposite layers of the diaphragm either move towards or away from each other depending on the direction of the current, thereby moving air and creating sound. 

By distributing the diaphragm area over several layers and implementing a curved shape, AirBlade avoids the typical beaming problem of traditional drivers while achieving higher power handling, reduced distortion and better air coupling due to its large diaphragm surface area. The transducer’s radiation pattern can also be tailored to specific requirements of the application it is driving.

Arya Audio Labs has manufactured in-house since its inception. It uses advanced prototyping tools including 3D printing, 5 axis CNC machines and state-of-the-art measurement facilities. The company started shipping the AirBlade directly to customers at the beginning of 2020 and it proved a very popular seller. It is now looking for ways to improve and speed up the processes to help deliver highest quality products.

The audio market has been on the rise for the past couple of years, with an abundance of streaming services available as well as vinyl records experiencing a come-back. The company’s technology has been especially well received at the high end of the market and in the automotive audio sectors, two markets that are worth over £1 billion a year alone.

Dominika says of the Enterprise Fellowship: “I come from an academic background, where it’s natural to focus your efforts on developing technology and forget that you are actually trying to run a business! The Fellowship has given me an excellent opportunity to shift that mindset, and strike a good balance between the two.”

Traction 

2018 – Arya Audio Labs debuts at High End Munich as a Newcomer
2018 – First product, RevOpod, starts shipping
2019 – RevOpod receives Best of 2018 award by Mono and Stereo
2019 – AirBlade loudspeaker starts shipping to original equipment manufacturing partners
2020 – AirBlade loudspeaker becomes available for end customers

Visit their website: www.arya-audio.com   

Grakn Labs have developed a system called Grakn, an open-source intelligent database. Grakn handles large amounts of complex data through knowledge engineering – commonly known as knowledge graphs. It is the world’s first database with a schema powered by a knowledge representation system and uses a query language called Graql to enable this.

Grakn’s database technology provides the knowledge base foundation for artificial intelligence systems used in various industries, including financial services, defence and security, life sciences, robotics and cyber security.

Tomás Sabat is the Chief Operating Officer at Grakn Labs, responsible for generating sales, marketing and finance. He develops strategic relationships with clients who can benefit from Grakn’s ability to easily model, query and analyse complex information in a simple and logical way.

Tomás joined the SME Leaders programme in 2018. He says: “The scheme has given us an introduction to investors and provided leadership and media training. It has also supplied us with networking opportunities with other engineering businesses in the UK.”

Grakn Labs has doubled its staff in two years and raised £2.4 million of funding. It is now ready to produce at scale, both in terms of commercial adoption as well as scaling its technology. 

MySense Ltd has created a wellbeing analytics platform for people with declining health, enabling them to live independently in their own homes. Its system uses a network of wearable and fixed sensors in a property. Using artificial intelligence and the internet of things, the platform learns a person’s pattern of behaviour, while building up an informed picture of a user’s health condition.

Thousands of data points track a user’s nutrition, hydration, independence, activity and overall sense of wellbeing. A smartwatch records heart rate and step count, while an easy-to-use dashboard displays the information, highlighting any unusual patterns and triggering a notification to a nominated responder.

MySense monitoring data doesn’t record video or sound as there are no cameras or microphones. The real-time data allows family members, friends, clinicians and care givers to stay informed about a person’s wellbeing. Detailed evaluations through use have shown significant reductions in GP appointments, 999 calls and unplanned hospital admissions.

Lucie Glenday is Co-Founder and Group CEO of MySense. Lucie joined the SME Leaders programme in 2021 and is looking forward to two specific programme initiatives. She says “Having a mentor will allow me to talk through decisions the company is making and how to position these in order to gain maximum impact. And I’m hoping that learning at one of the world’s top universities will further develop my leadership skills.”

MySense consists of data scientists, engineers, testers, clinical researchers and a commercially-experienced management team. The company is growing quickly and is now working on raising brand awareness, building a research partnership network and preparing its platform for international markets.

When Mohammed Belal became an SME Leader in 2019, he had already co-founded MIRICO, a company developing laser sensing technology for real-time gas sensing. Now, Mohammed is setting up a new venture, Celestial Eye, a spin-out from RAL Space.

Celestial Eye is developing innovative space-borne sensors deployed in a constellation to obtain global high-precision weather data. The project is working on providing high-resolution profiles of moisture and temperature across the atmosphere. This will improve the observation and forecasting of weather patterns as well as monitoring climate change.

Mohammed credits the SME Leader programme with honing his entrepreneurial skills, He says: “I gained valuable insights from other SME Leaders about startups and networking. It also helped me develop my management capabilities and the fundamental skills required to set up and scale businesses.”

Mohammed is responsible for setting up the venture and defining business strategy for the launch and development. He is currently focused on raising capital to build an engineering team and launch its first satellite. The mission will improve observations of weather systems, and more accurately forecast extreme events.

Problem:

Jelly Drops are 95% water sweets, designed to help people with dementia stay hydrated. Initially developed by Lewis for his Grandma Pat, Jelly Drops turn something that can often be a difficult task into the highlight of the day.

Solution:

Many people with dementia no longer feel thirst, don’t equate drinking with quenching thirst, or don’t recognise cups or have the dexterity to pick them up. To understand this better, Lewis lived in his grandma’s care home for a month. He realised that while many residents struggled to hydrate themselves independently, they all loved sweets.

Dementia is the leading cause of death in the UK, currently effecting more than 850,000 people. This is expected to reach over 1.5 million by 2040. Jelly Drops are bright, easy to pick up, vegan, sugar-free (with no laxative effect) sweets, that contain natural colours and flavours, and are shelf-stable. They enable people with dementia to hydrate themselves independently and with dignity.

The company has just launched and its main focus is to reach people with dementia that are suffering from dehydration. Jelly Drops will do this through care homes, but also via an online shop to serve people out in the community. Once established in the UK, Jelly Drops plans to ship the products abroad, and already has a waiting list of 35,000 in the US.

Jelly Drops hopes to diversify its product range to help a wider audience with hydration and other critical dietary requirements.

Jelly Drops was the first company accepted onto the Alzheimer’s Society Innovation Accelerator Programme and the project recently won the Outstanding Dementia Care Innovation Award at the Dementia Care Awards. Other awards include Pitch@Palace Global - Winner, European Investment Bank - Social Innovation Prize, EIT Food – UK Winner, EIT Health - Future of Health Award, Innovation Forum - IMAGINE IF! Global winner, Pitch@Palace 11.0 - Audience Vote and People’s Choice Award, Huawei - New Working Order Bursary and the Meaning-Centred Design - Student Healthcare Winner .

Traction:

•        July 2018: Jelly Drops won the RCA’s Helen Hamlyn Centre for Design - Snowdon Award for Disability and Imperial’s Dyson School of Design - DESIRE Award.
•        Aug 2018: Online videos of Jelly Drops receive over 100 million views and features on the BBC, Sky News and many others.
•        Sept 2018: Just Giving page is set up on the company’s behalf and raises almost £10,000.
•        Jan 2019: Jelly Drops features on the TEDX stage in California.
•        Feb 2019: Partner with Alzheimer’s Society on its innovation accelerator programme.
•        March 2019: Raised investment.
•        Aug 2019: Develop Market ready product to start user testing.
•        Feb 2020: Production facility completed and starts supplying people on the waiting list.
•        March 2020: Raised further investment.
•        July 2020: Website launches to the public.
•        Nov 2020: Win Outstanding Dementia Care Innovation Award and produce its millionth Jelly Drop.

Problem:

The value of lost productivity due to knee osteoarthritis is estimated to be $100 billion annually in the US alone. Efforts need to be made to improve recovery from osteoarthritis and musculoskeletal injury.

Solution:

Zappt coordinates targeted neuromuscular activation with the patient’s movements to enable joint offloading in osteoarthritis and dynamic bracing in musculoskeletal injury. Joint offloading involves shifting pressure within the joint away from a region of damage towards a healthier portion whereas dynamic bracing involves selectively applied support in situationally specific load cases.

It plans to carry out user trials with the Royal Dutch Football Association, the KNVB, in the Netherlands. This will be the first major field trial of its novel prototype. Zappt hopes to use the insights gained to hone the product and make sure it performs as partners require.

Traction:

•         2018: Wellcome Trust Musculoskeletal Accelerator funding.
•         2019: Collaboration with Royal Dutch Football Association.

Anne is a prominent venture capitalist and European technology investor who has been Chief Executive of Amadeus Capital Partners from 1997. As a co-founder in the organisation, Anne’s role combines her experience as a scientist, operating manager and venture capitalist.

Anne began her career in manufacturing with Cummins Engine Company before moving into investment as a business angel. She was also Chief Operating Officer of Virtuality Group, which had been one of her investee companies.

Anne has held a number of high profile advisory positions, having served as Chairman of the British Venture Capital Association in 2004, and as a non-executive director of the UK Technology Strategy Board from 2005-2012. In 2008 Anne led the establishment of the Glover advisory committee for the Chancellor of the Exchequer, reporting on government procurement from SMEs. She is also a member of the European Research and Innovation Advisory Board. Anne was awarded a CBE for services to business in 2006 and was elected an Honourary Fellow of the Royal Academy of Engineering in 2008.

John is a highly experienced executive and senior consultant across the oil and gas, renewable energy and digital technology sectors, as well as a member of many international boards. He has significant interest in the commercial and technology challenges that energy transition presents, especially as these intersect with corporations’ digital transformation.

John is currently Chair of the Gresham House Energy Storage Fund Board, which specialises in the commercialisation of grid-level storage investments. The company is now the largest energy storage fund in the UK and is the market leader. In November 2018, the company listed on LSE at £100 million and at the end of 2020 had a market cap of around £250 million; it is on a strong growth trajectory and should double in size over the next 24 months.

Until April 2019, John was an advisor to the Board of ACWA Power International (Riyadh), the largest independent power producer in Saudi Arabia. Until December 2017, he was on the Board of the ASX-listed Carnegie Clean Energy, based in Perth, WA. He is also an investor and Board member of Global Integrity, a cybersecurity software and cyber consultancy firm based in Washington DC.

John spent more than 25 years working at BP, the last 10 of which were spent at the corporate executive level in various roles including:

• President of AIOC (Azerbaijan Intentional Operating Company) based in Baku and responsible for the ca $8 billion Caspian Development
• Group Chief Information Officer, which involved leading significant integration and transformation programmes associated with BP’s industry consolidation campaign with Amoco, Arco, etc. and in leading the corporation’s digital transformation
• leading development of the corporation’s investment activity into the digitisation of trading systems, automated marketplaces and green energy companies
• group-wide physical and cybersecurity oversight, including global emergency response.

In his early career, John worked on the design and construction of nuclear power generation plants in UK.

Since leaving BP, John has been active as a senior advisor to blue chip global consultants specialising in the energy sector, energy transition and corporate digital transformation.

John serves on the Royal Academy of Engineering’s Enterprise Committee.

Professor Norman Apsley OBE FREng recently retired from 18 years as founding Chief Executive of Catalyst Inc (formerly Northern Ireland Science Park), steering the organisation from idea to reality. The NI Science Park was a key first step to transform the near derelict H&W shipyard into the innovation district for Belfast. He had spent the previous two decades at the Royal Signals and Radar Establishment (now QinetiQ Malvern), where he had researched a wide variety of microwave and optical devices, publishing some 70 scientific papers and patents during his scientific career. He joined management in 1990, rising to Director Electronics and Site Director for the Malvern cluster in the then Defence Research and Evaluation Agency by 1995.

In 2011, he was elected as a Fellow of the Royal Academy of Engineering, just as he finished his term as Vice-President (Business and Innovation) of the Institute of Physics. He has been an active Enterprise Committee member from the beginning and continues to contribute to its various programmes as reviewer, mentor and on steering groups, most lately the SME Leaders’ Award.

Norman also supports the international work of the Academy. In 2018, he became Chair of the Academy’s Newton-funded project, Leaders in Innovation Fellowships (LIF), which works in all 16 Newton Fund countries. Alongside in-country partners, LIF helps innovators with technology to tackle their country’s sustainable development goals launch startups. Over the past few years, LIf fellows have been built into a thousand strong, peer-to-peer support group across the world.

At home, Norman chairs the Local Economic Development Company serving South and East Antrim and consults occasionally for both public and private sector. In 2012, Norman was awarded an OBE for his contributions to science and economic development. In 2019, the honorary degree of Doctor of Science (Econ Sci) was conferred by Queens University Belfast. In the same year, he was awarded the Max Rainey Medal for service to the Polymer Industry of Northern Ireland. He is looking forward to Belfast becoming the first (of many) spokes to the Enterprise Hub.

Professor Neville Jackson FREng has spent nearly 40 years in industrial R&D, primarily in transport and energy systems. He has experience in managing complex R&D portfolios and spinning out new technologies into commercially funded startups. 

He currently chairs both the RAC Foundation and the Institute of Digital Engineering Advisory Board and is also a non-executive director of the UK Advanced Propulsion Centre. He also chairs the Royal Academy of Engineering’s steering group for the Increasing engineering business R&D investment project.  He has been a member of the UK Automotive Council since it was formed and is a member of the Strategy Team, chairing the R&D/Horizon Scanning working group. 

From 2009 until 2019 he was Chief Technology and Innovation Officer for Ricardo plc. He has co-ordinated and authored a wide range of technology roadmaps at national and European level, defining the potential, and technology pathways for transport energy, propulsion systems, future vehicle electrical/electronic architectures and digitalisation/virtual product development. 

A graduate of Imperial College London, he is also a visiting professor at the University of Brighton.  His past roles have included Chairman of the Low Carbon Vehicle Partnership, a six-year term as a member of the EPSRC Strategic Advisory Network, Vice Chair of the European Road Transport Research Advisory Council (ERTRAC) and a member of the Industry Delegation for the European Green Vehicles Initiative (EGVI).  He is also a Fellow of the US SAE and was elected a Fellow of the Royal Academy of Engineering in 2011.

Saeed is Technical Director at the prosthetic manufacturer Blatchford, winners of the 2016 RAEng MacRobert Award.

He has built a highly successful career based on outstanding innovation, product development and scientific research in the field of prosthetics. His work saw the company shortlisted for the Royal Academy of Engineering MacRobert Award in 2010.

Saeed has provided invaluable advice to emerging innovators in his field, such as negotiating with investors, creating new business cases and establishing alternative investment return strategies,  IP issues, and how to identify new needs and opportunities in the market to develop a road map of future products.

He  was elected a Fellow of the Royal Academy of Engineering (FREng) in 2012.

Professor Daniel McCaughan OBE FREng is a former industrial executive who has held senior management and board-level positions in the electronics, telecommunications and defence industries since the early 1970s. He was a partner in two VC Groups, Chief Scientist of Bell Northern Research/Nortel Technology, Technical Director of GEC’s Electronic Devices group of companies, President of CDT Ltd, a Senior Principal at RSRE, Malvern and a Member of Bell Labs Technical Staff. He is an Emeritus Partner of the leading Irish Venture Capital fund Kernel Capital Partners. 

He chaired the former Technology Board for Northern Ireland (a predecessor of InvestNI), was a member of the main board of DHSSPS, the Northern Ireland Health Service, co-chaired the UK Home Office Science Advisory Committee with the Permanent Secretary, and chaired UK Foresight in IT, Comms and Media and was an Honorary Professor of Queen’s University Belfast.

Daniel has a wide range of experience in technology-based businesses thanks to his career at high executive level in Venture Capital, large and small companies, government departments and universities. This background provides him with unique skills as he has dealt with a wide variety of customers and led major technical projects from component to system level, with insight into the evaluation of technical product plans and projects, company business planning and development, preparation of companies for investment, and Venture Capital.

Dr McCaughan has doctorates in both physics and engineering, has been awarded numerous patents and has published over 100 papers and book chapters in both technical and managerial subjects. He was elected a Fellow of the Royal Academy of Engineering in 1992 and the Irish Academy of Engineering in 1994.

Professor Dick Whittington FREng is an entrepreneur, business mentor and investor, focusing on the software industry and digital marketplaces, with over 30 years of experience in business. His experience has included co-founding a successful international software business recognised in UK through three Queen's Awards covering both innovation and international trade.

In 2012 he was elected Fellow of the Royal Academy of Engineering where he plays an active role, including as a mentor for early-stage technology startups and spin-outs through its highly successful Enterprise Hub. He is also an active mentor and angel investor within several London and regional technology accelerator programmes, and is Honorary Professor of Business Innovation at the University of York.

Prior to pursuing business interests, Dick lectured in computer science at the University of York. He managed a successful research team and published several research papers and books. His latest book Digital Innovation and Entrepreneurship (Cambridge University Press, 2018) provides an introduction to digital business for STEM students and early-stage entrepreneurs.

Paul Taylor FREng has led the delivery of some of the most demanding national security programmes in the UK, operating at the very highest levels of government. He is uniquely qualified to understand the evolving threat environment, as well as having an exceptional track record of driving and delivering change in complex organisations. Paul’s contribution to the world of science technology was recognised by his election as a Fellow of the Royal Academy of Engineering in 2013, where he now sits on its Engineering Policy Committee.

Paul is Deputy Managing Director at AWE plc, where he is responsible for providing the AWE Board and UK Ministry of Defence (MOD) with assurance of delivery of the £1 billion per annum nuclear warhead programme. Prior to this, he was Director General of Technology and Chief Information Officer in a central government department, where he was a member of both ExCo and the main board.

He held the position of Director General of Strategic Technologies and then Director General of Equipment in MOD, and Senior Responsible Owner for the UK’s Future Nuclear Deterrent. Paul was the first Chief Executive of the Defence Science and Technology Laboratory (DSTL). The post carried responsibility for all elements of defence research and the 3,000 staff that were retained within government following the split of MOD R&D activities into QinetiQ and DSTL.

A member of several government technical advisory committees, Paul also chairs the Advisory Board of the Imperial College Institute of Security Science and Technology. He is currently advising and exercising several global retail and investment banks at board level, helping to address their cyber and information protection challenges. Paul sits on a number of bank board risk committee advisory panels.

Formerly the UK Innovation Director for Atkins, Elspeth is the CEO and Founder of IAND, a digital platform that helps major enterprises manage multiple suppliers. 

Initially graduating as a chemist, Elspeth later turned her hand to transport and urban design, demonstrating business and technical leadership on over 100 transport planning projects both nationally and around the world.

Elspeth chairs the Enterprise Hub’s Innovators Network and is a judge for the Hub’s Launchpad Competition. She is also a member of the Royal Academy of Engineering’s Diversity and Inclusion Committee.

In 2017, Elspeth was awarded a Member of the Order of the British Empire (MBE) for her services to Engineering and Enterprise.