We aim to foster a culture of entrepreneurship, innovation and success among engineers in the UK, creating economic growth and societal impact. At the heart of how we do this are the Hub Members, the promising entrepreneurs who we support through our programmes, and our Hub Mentors, the business leaders who volunteer their expertise and time to help the Hub Members succeed.
From manufacturing to medtech, our Hub Membership is made up of some of the UK’s most innovative entrepreneurs. But don’t just take our word for it: read more about our Hub Members to see how they are, without exaggeration, changing the world.
Losing your eyesight is one of the most devastating things that can happen to a person.
Some forms of vision loss that affect the retina, such as age-related macular degeneration (AMD), or diabetes can be treated. This requires monthly injections into the eye for at least five years. The treatment works well for most people but requires regular outpatient visits and there is a small risk of additional complications from the injection process itself.
There is a real need to make treatments better, safer and more convenient.
I-Daruma has developed a technology that takes the same treatment and makes it possible to deliver the currently injected drugs as eye drops instead. It works by creating short-lived nanoparticles that are mixed with the drugs. These then dissociate at the target tissues, releasing the drug. The nanoparticles are made from compounds that naturally occur in the body and are well-tolerated, giving the technology the advantages of nanoparticle delivery without the toxicity associated with current nanoparticles.
The eye drops will address several issues with the current treatment regime. While injections must be administered by trained healthcare professionals in a clinical setting, eye drops can be administered by the patient themselves anywhere, resulting in large healthcare cost savings.
Worldwide, there were 14 million intravitreal injections performed in 2018 and it’s a number that has been growing 20% year-on-year. The drivers of treatment are the ageing global population and metabolic disease such as diabetes. About one third of people living with diabetes will suffer from diabetic retinopathy. Age-related macular degeneration (AMD) is also a leading cause of vision loss in Europe and the US. Currently, 196 million people are estimated to be affected by AMD globally, a figure expected to hit 288 million by 2040.
In the next 12 to 18 months, Naa Dei anticipates applying for InnovateUK Grant funding and looks forward to completing pre-clinical trials and having a dossier for approval for clinical trials.
2020 – Awarded a Royal Academy of Engineering’s Enterprise Fellowship.
2020 – Piloting trials of technology with a pharmaceutical company.
“[The Enterprise Fellowship] has opened my eyes to what goes into turning a neat idea into a business and has equipped me with tools to do so. It’s an amazing network of people at different stages of their enterprises, and I’ve found it very supportive.”
Sustainable construction demands better management of social and environmental impact. To achieve this, reliable, efficient tools are needed to make sense of large volumes of data across the range of related fields.
Qflow is a cloud-based platform that enables construction projects to manage their environmental risk and stay compliant with environmental standards.
Qflow brings together machine learning and the Internet of things to capture and analyse environmental data, making it easier to identify and manage risk. This increases productivity and reduces cost while positively impacting the built environment.
The technology connects to existing, on-site systems to automate real-time data collection and analysis. This leads to better informed decisions, more accurate predictions and the ability to generate standardised reports. It reduces costs associated with delays and mitigation processes caused by unmanaged environmental risk.
Trials have shown that Qualis Flows’ solutions can improve data capture against existing competitors by over 100%. Four pilot programmes are scheduled for spring 2019 to further validate the technology’s use in monitoring aspects such as waste, noise, air quality and vibration.
Brittany Harris brings significant experience in civil engineering as she leads a multi-skilled team of engineers, environmental professionals and software architects as Qualis Flow brings its solutions to market.
The array of switches, buttons, wheels and controls that help us to interact with electronics all rely on bulky and complex networks of sensors that can cost a lot to create.
TG0 has developed a new technology for making interactive 3D controls that are ergonomic, intuitive and engaging. Its solutions replace complicated networks of electronic sensors with one uniform, flexible, touch-sensitive material.
Driven by artificial intelligence algorithms and advanced signal processing, TG0’s platform technology can accurately detect variations in touch across a single flexible surface. This allows its material to easily sense pressure, location, speed, direction and movement allowing users to engage in more intuitive ways.
As Co-Founder, Ming leads research and development for the technology’s hardware. TG0’s seamless, interactive surfaces can be used in a range of applications including tactile gaming controls, car dashboard controls and ergonomic computer peripherals such as keyboards, amongst many others.
TG0 is also exploring how its technology can be used to make interactive products that are more accessible for the visually impaired.
Since its launch in 2016, TG0 has worked with high profile brands and manufacturers in the consumer and automotive sector and built a patent portfolio with more than ten international patent entries to date. A rapidly growing team is helping the company to expand and target a range of industries including sensor-embedded industrial robots, wearables, gadgets and underwater electronics.
"Getting to grips with a whole new mechanism for sensing and control doesn’t come naturally when you’ve spent your life learning to use another system."
The flexible and printed electronics markets are working towards having speedy, defect-free manufacturing processes. To achieve this, they need new inspection systems that allow live testing and enable real-time quality assurance without stopping production.
Dr Muhamedsalih has helped create a multi-wavelength polarising interferometer (MPI) for in-line surface metrology. It operates at the micro/nano-scale level and can be used for real time inspections of moving surfaces. The interferometer is combined with a software method to handle larger amount of data for surface analysis without direct interaction from the operator.
The system detects and characterises defects. This means that manufacturers will be able to understand what causes faults and take measures to correct them. Importantly, the technology is sufficiently robust to be used on the shop floor.
Hussam is now working to validate the MPI’s performance with world-leading manufacturers and research centres. His innovation is being tested by the UK Catapult National Centre for Printable Electronics – Centre for Process Innovation. His proof of concept system should reach Technology Readiness Level 9 before the end of 2021 and be ready to launch and available to buy soon after.
Analysts have forecast that the global metrology market will grow to over $600 million by 2023 in the traditional manufacturing market. Hussam’s technology also fits into the printed and flexible electronics markets, which are predicted to grow to $77 billion by 2023.
For Dr Muhamedsalih, the Enterprise Fellowship experience has: “allowed me to structure my business model and test it out by intensive direct interaction with industry and potential clients.”
Women deserve a better way of getting professionally fitted for bras. The lack of care and proper training within the bra industry means that bra-sizing confusion is a never-ending debate. Inefficient practices result in 80% of women wearing bras that don’t fit properly and billions of pounds lost every year in size- and fit-related exchanges and returns.
Combining state-of-the-art computer vision with data from real-life women (our co-creators), Brarista is bringing professional bra-fitting to bra-wearers’ homes. Its technology makes it possible for clients to find their best fit across product lines simply by using their phone camera.
Researching this technology to ensure its usefulness and accuracy is technically complex. Brarista is working hard to continue building, testing, and improving the current prototype before conducting technical trials.
The ongoing pandemic gave Brarista an opportunity to collaborate with Boost Innovations Ltd to apply its technology to fit breast prostheses online for breast cancer survivors (classified by the NHS as a higher-risk group). Research shows that getting bra-fitted using a tape-measure results in a 70% inaccuracy rate, but this is still the most popular method used by high street bra-fitters and online bra-fitting guides. Brarista hopes that its technology will improve the accuracy by at least 40% to be on par with professional bra-fitting by eyesight.
2018 - Won the Most Innovative Idea at the UCL Innovation and Enterprise Launch Programme
2019 - Team formation and acquired trial interests from the industry
2019 - Selected as a startup to be mentored by DeFine Network EU (a European Commission-funded FashionTech Community).
2019 - Selected as one of seven startups to join Women in AI & Data in Israel with InnovateUK
2019 - Highly Commended Award at the Academy’s Enterprise Hub Launchpad Competition Final
2020 - Crowdfunded successfully and matchfunded with NatWest Back Her Business
2020 - Acquired a new research client to apply its technology to fit breast prosthesis online
To find out more abut Brarista visit https://www.brarista.co/
“[The programme has helped by] providing the network of supporters, coaches and mentors that help me grow as an entrepreneur.”
For decades, satellites have been getting smaller but the rockets that launch them haven’t. Most active vehicles are still designed for historically large satellites and this is forcing a new generation of SmallSats to rideshare on enormous rockets in an expensive system of compromise.
Of the small satellites forecast to be launched between 2021 and 2030, 70% are predicted to fall in the under 250-kilogram weight class. However, launch vehicles that can operate at this weight lack appropriate propulsion systems. There is a clear market demand for dedicated launch vehicles that can take small satellites exactly where and when they need to go, but the fundamental technical challenge is that rocket engines and their associated pumps and turbomachinery are incredibly difficult to scale down. Attempts to scale down existing technology commonly result in spiralling costs and complexities.
Protolaunch believes that the right engine is the key to unlocking a successful microlauncher, and aims to supply that propulsion. It is developing an engine based around a novel thermodynamic cycle designed specifically for small payloads from the outset. This is possible because of its core engine technology, which acts as the enabler for a new type of launch vehicle.
The Protolaunch engine has three key advantages:
“Over the next 12 to 18 months, we look forward to working with the Royal Academy of Engineering as we build our long-term commercial strategy and start to engage with larger aerospace partners and customers.”
Better intraoperative guidance can help reduce patient morbidity and healthcare costs across surgical specialties. For example, brain tumour patients undergoing surgery have significantly improved outcomes and increased life expectancy if complete tumour removal is achieved. However, maximal resection needs to be balanced with the goal of healthy tissue preservation in order to minimise patient risk and neurological impairment. Yet, even with the most advanced current techniques, intraoperative decisions with potentially life-changing consequences are still based on the surgeon’s subjective visual assessment.
Hypervision Surgical has designed an AI-powered imaging system for wide-field tissue characterisation that attaches to and enhances existing surgical equipment. For the first time, surgeons will have real-time actionable information on tumour and critical brain structure margins during surgery. In addition, their system can monitor vital physiological tissue properties thereby increasing surgical precision and patient safety while optimising resection.
As a King’s College London spin-out, Hypervision Surgical is embedded in the St Thomas’ MedTech Hub and has close ties with King’s Health Partner hospitals. Further clinical studies are scheduled to develop and evaluate their technology to achieve commercial readiness.
Dr Ebner was awarded an Enterprise Fellowship award in 2020 to support him as he leads Hypervision Surgical in bringing its innovations to market.
Modern surgical implants use ‘press-fit’ and are hammered into place by the surgeon, creating friction that holds the implant in place. If the surgeon impacts the implant too rigorously, the bone may be over-stressed and fracture.
Bone fracture during hip replacement surgery affects between 2% and 8% of patients. If fracture occurs the patient is seven times more likely to need expensive revision surgery and twice as likely to die from complications.
Additive Instruments’ technology is a ‘smart’ surgical tool that can sense the force being applied to the instrument and adjust it to reduce the chances of fracture. By reducing the variation in impaction force, the technology also reduces the learning curve for new surgeons – reducing the likelihood of fracture through inexperience.
In the UK and US, 400,000 hip replacement procedures are conducted every year. If a conservative estimate of 2% of these surgeries were to result in fracture, 8,000 patients would suffer a painful and debilitating injury each year, most requiring revision surgery at great expense. These surgeries are estimated to cost £25 million every year.
Additive Instruments’ technology has been proven in the laboratory, so its next key milestone is to validate the product in a clinical environment, first with specimens and subsequently with live patients. Once the efficacy of the product has been proven, Additive Instruments will apply for a CE mark – a key achievement for any medical device.
Early laboratory development was supported by the Wellcome trust with a product translation award. Following the support of the Royal Academy of Engineering’s Enterprise Hub, Additive Instruments has been awarded an i4i (invention for innovation) award from the National Institute for Health Research (NIHR). This funding will help it achieve its goal of first clinical usage within the next two years.
“The real value of the Enterprise Fellowship is in the soft support I have received. Business coaching, workshops to develop interpersonal and planning skills, as well as brilliant insights from my mentor have all been hugely useful as Additive Instruments starts its journey into the commercial world.”
Commercial drones are now being used for several different roles such as mapping farms, inspecting buildings and search-and-rescue operations. Most commercial drone automation software on the market is generic, meaning drone operators and enterprises requiring customised solutions are forced to use many different types of software to get their job done. This becomes incredibly expensive and unreliable.
Hammer Flights Ltd is the world’s first adaptive flight automation software for unmanned aerial vehicles. It is highly versatile, supporting many different types of flight automation and yet is extremely simple to use. Using modular software architecture and APIs , the software morphs according to the task at hand.
Hammer aims to empower every drone operation in the world with adaptive flight automation to make their operations more productive, creative and safe. Its next key milestone is to understand how it can scale its enterprise offerings over the next 12 to 18 months.
The commercial drone industry is currently worth $13 billion and is expected to grow to $45 billion by 2025. A lot of this growth is attributed to enterprises rapidly setting up in-house drone teams and integrating drones into their existing workflows. Each one of these businesses will be looking for a customised flight automation solution that adapts to the needs of their business.
Hammer is currently grant funded by Ordnance Survey – the UK’s largest mapping agency – and the Royal Academy of Engineering through its Enterprise Fellowship programme. It has also formed strategic partnerships within the drone ecosystem.
“The Enterprise Fellowship has provided us with an amazing network of fellow entrepreneurs and mentors that we can learn from throughout our journey.”
What makes us different is the Academy’s Fellows and our wider Mentor network – an unrivalled community of the UK’s most successful industry leaders, technology experts and entrepreneurs. Find out more about our Mentors and their areas of expertise.
Professor Clive Buckberry FREng is the Chief Engineer and Technology Officer of Quanta Dialysis Technologies, a company that provides dialysis systems for renal patients. He has been in the role since Quanta was established in 2008, was a co-founder and has been an integral part of the original team that has since raised over £110 million in venture capital funding following its launch.
Clive has a broad remit to direct and influence technology development and its implementation within Quanta. He has also had direct responsibility for the clinical evaluation and regulatory strategy of the haemodialysis machine, and the engineering development of the extracorporeal pathway and currently leads a team of over 50 engineers.
Previously Clive worked for the BMW group with responsibility for the vehicle physics department. In 2001, he became an honorary professor within the Department of Engineering and Physics at Heriot-Watt University and in 2011 was elected a Fellow of the Royal Academy of Engineering.
Professor David Cebon FREng is a professor of mechanical engineering at the University of Cambridge and Director of the Cambridge Vehicle Dynamics Consortium and the Centre for Sustainable Road Freight. He also leads the engineering department’s Transport Research Group and its research theme 'Energy, Transport and Urban Infrastructure'. His research covers the mechanical, civil, and materials aspects of road transport engineering.
He has authored or co-authored more than 200 papers on dynamic loads of heavy vehicles, road and bridge response and damage, advanced suspension design for heavy vehicles, heavy vehicle safety and mobility, heavy vehicle energy consumption and decarbonisation, and the micromechanics of asphalt deformation and fracture.
In 1994 David co-founded Granta Design Ltd, the world’s leading provider of materials information technology, with Professor Mike Ashby CBE FREng FRS. David led the company as its managing director until 2019, when it was acquired by Ansys Inc. He is now the Chief Materials Technologist at Ansys.
David was elected a Fellow of the Royal Academy of Engineering in 2005.
"I lead an active research group concerned with the design and dynamics of heavy vehicle suspensions, road damage and the micromechanics of asphalt failure. I also have interests in the use of computers in engineering design and education."
Dr Supti Sarkar leads the Technology and Investments Group at PwC. She is responsible for the commercialisation of new tech ventures across the firm, and works with in-house entrepreneurs to get their products market ready.
Supti was formally a management consultant at PA Consulting, where she worked with international and regional governments to support their trade and investment strategies. She was also part of Mayor Sadiq Khan's 2016 delegation to Chicago and New York as part of her role in supporting high growth companies entering the US market for the first time. Supti holds a first class degree and PhD in engineering from University College London and is mum to an eight-year-old daughter.
Dr Douglas C Anderson OBE FREng FRSE has a 40-year business career covering almost every aspect, at every level, of healthcare technology product design and product commercialisation processes.
Having trained in industrial design engineering (Edinburgh Napier University 1974), Douglas progressed from hands on designer to the management of design in the high-tech arena.
Using his consulting company Crombie Anderson as a base for innovation and incubation, he subsequently spun out three other high-tech startup companies, two of which became publicly traded business operating in medical fields.
Douglas was the prime mover in these businesses by leading both the innovation and commercialisation processes, including raising over £40 million in private and institutional funding prior to floatation. Today he is internationally recognised for his innovation and entrepreneurial experience and is a regular keynote speaker at healthcare and business congresses around the world.
In 1990, his five-year-old son Leif suffered a spontaneous retinal detachment that went undetected until it was too late to treat. Douglas was struck by the limited capability of diagnostic tools available to practitioners to examine the retina and decided to address this issue. He built a dedicated research team, which led to the formation of Optos plc, a business funded by Archangel from the outset.
Optos succeeded in designing and patenting a scanning laser ophthalmoscope: the world's first ophthalmic device that enabled eye care professionals to capture a digital ultra wide-field image of the almost the entire retina in a single scan. The new method of examining the retina, marketed as the optomap® Retinal Exam, is now offered as the preferred standard of care by tens of thousands of eye-care specialists globally. Over 200 million optomap® retinal exams have been conducted worldwide and a number of novel diagnostic techniques added to improve the understanding and treatment of a wider range of conditions that have been historically difficult to manage.
In 2006 Douglas was awarded an OBE for services to healthcare. Douglas was elected a Fellow of the Royal Academy of Engineering in 2013.
David is an investor and CEO with companies based on technology and innovation.
After a degree in electrical engineering at the Technion and an MBA from INSEAD, David worked his way to senior management and board level in a wide range of sectors including sustainability, construction, life sciences, manufacturing, mobile telephony, cyber security and software. His broad experience ranges from startups to public companies, from turnaround missions and crisis management to business development and growth.
David is deeply involved in the UK startup space, as a member of UKBAA, VCs, EIS funds and university angel groups, and is an active mentor with the Royal Academy of Engineering and Imperial College London’s IVMS programme. He also serves as a non-executive on the board of directors of Kerur Holdings (a public company), the board of governors of the Technion, as an advisor with the US accelerator Silicon Catalyst and the board of trustees of Hadassah UK.
He believes that success comes from a culture of excellence, a multidisciplinary approach, and that the boundaries between B2B/B2C and startups/LargeCo are increasingly blurred.
"Startups challenge and can defeat established companies. An explosion of new technologies will accelerate this trend. Large companies cannot afford to be on the defensive, they must proactively adopt a startup culture. But startups must also learn to be humble and pragmatic, build structures, communicate at a senior level, and strive to serve all their stakeholders, clients, staff, investors, and society as a whole. A fusion of cultures is now pivotal to success."
Richard joined sustainability investment focused Earth Capital Group in 2009 and has worked both on the group’s investment in investment managers and direct growth company investments, including most recently the fund’s investments in SoftIron and Propelair. He takes a leading role in promoting technology transfer opportunities across the group’s international offices.
Prior to joining Earth Capital, Richard was an Investment Director with IBIS Asset Management Ltd, a London-based captive advisor to a large Caribbean conglomerate. Richard was earlier a senior manager in the London office of L.E.K. Consulting, a global strategy consultancy. During his five years with LEK he provided due diligence advice, in numerous large cap and mid-market private equity deals, and advised corporate clients on corporate strategy, business unit growth strategy, process redesign and cost reduction programmes.
A chartered engineer, his early career included successful engineering, operations and customer support management roles with Ford Motor Company and Visteon Corporation. Richard holds an MBA with Distinction from INSEAD and MEng and MA (First Class) degrees in engineering from the University of Cambridge. He is a chartered member of the Chartered Institute of Securities and Investment, and a Chartered Member of the Institute of Engineering and Technology and a Sainsbury Management Fellow.
Dr Andrew Hosty FREng is an international leader with over 15 years of non-executive board experience and 30 years of executive and management experience, spanning private equity, UK Plc and global blue-chip corporates. He is non-executive director of a companies including: RHI-Magnesita, the global leader in the manufacture and supply of refractories; James Cropper Plc, who create some of the world’s most distinctive and technically advanced paper products; and Rights and Issues Investment Trust Plc, a fund that focuses on small cap UK industrials.
Andrew is Non-Executive Chairman of mOm Incubators ltd, a pre-revenue startup developing low-cost baby incubators for crisis zones. He is also Non-Executive Chairman of Nexeon ltd, a company developing next-generation cathode materials for lithium-ion batteries. From 2016 to 2018 Andrew was the CEO of the Sir Henry Royce Institute, the UK's home of advanced materials research and innovation. He was Chief Operating Officer of Morgan Advanced Materials, and served on the Plc Board as an Executive Director from 2010 to 2016.
From 2013 to 2016 he served on the board
of Consort Medical Plc, a healthcare company focused on developing advanced
delivery technologies, formulation and manufacturing solutions for drugs. He is
a Fellow of the Institute of Materials, holds a PhD from the Faculty of
Engineering at the University of Sheffield and is a Fellow of the Royal Academy
of Engineering (2011).
Chris McIntosh joined Methera Global as CEO in 2017. The company’s vision is to enable the delivery of digital applications to rural and underserved communities worldwide via a resilient constellation of Ka band MEO satellites. He previously spent seven years as CEO of ViaSat UK where he was responsible for the inception and growth of ViaSat’s UK satellite capabilities. Headquartered in the US, ViaSat are renowned as being one of the most disruptive players in the satellite communications and security domain.
Before joining ViaSat Chris was CEO of Stonewood Group, developers of state-of-the-art cyber products and services. He is a retired Lieutenant Colonel from the British Army and has worked within the challenging, high threat cyber and communications environment for over 30 years. He holds a BSc in computer science, MSc in design of computer systems and an MBA. He is a member of the UKspace trade association and the National Security and Resilience Consortium, and is a chartered engineer.
Roy Williamson has been helping companies see how their new innovations can disrupt markets for over 20 years.
For the past six years has been successfully helping early stage companies identify and define their strengths, enhance their uniqueness and develop their storylines to engage investors. Roy’s background is in engineering and cleantech and since 2013, he’s been supporting SMEs and entrepreneurs across a broad area of technologies and innovative business models.
Roy is an aeronautical engineer and started his career at Alstom, developing algorithms and models to estimate hardware costs of power generation gas turbines based purely on, often novel, thermodynamic cycles. He has assessed innovation ecosystems of the UK, published by the Organisation for Economic Co-operation and Development. He has also co-authored guides to support technology developers in the UK automotive sector assess technology readiness levels and help those in the biofuels sector to review pathways for second generation biofuels. He’s appraised novel technology solutions for blue-chip clients, developed proof of concepts and carried out due diligence activities to support investor decision making. He is passionate about the UK and knowledge-intensive companies, from software to deeptech.
Roy is Head of Origination at the Department for International Trade with relationships across the department’s teams, government and the UK’s innovation and investment ecosystem.