We aim to foster a culture of entrepreneurship, innovation and success among engineers in the UK, creating economic growth and societal impact. At the heart of how we do this are the Hub Members, the promising entrepreneurs who we support through our programmes, and our Hub Mentors, the business leaders who volunteer their expertise and time to help the Hub Members succeed.
From manufacturing to medtech, our Hub Membership is made up of some of the UK’s most innovative entrepreneurs. But don’t just take our word for it: read more about our Hub Members to see how they are, without exaggeration, changing the world.
Losing your eyesight is one of the most devastating things that can happen to a person.
Some forms of vision loss that affect the retina, such as age-related macular degeneration (AMD), or diabetes can be treated. This requires monthly injections into the eye for at least five years. The treatment works well for most people but requires regular outpatient visits and there is a small risk of additional complications from the injection process itself.
There is a real need to make treatments better, safer and more convenient.
I-Daruma has developed a technology that takes the same treatment and makes it possible to deliver the currently injected drugs as eye drops instead. It works by creating short-lived nanoparticles that are mixed with the drugs. These then dissociate at the target tissues, releasing the drug. The nanoparticles are made from compounds that naturally occur in the body and are well-tolerated, giving the technology the advantages of nanoparticle delivery without the toxicity associated with current nanoparticles.
The eye drops will address several issues with the current treatment regime. While injections must be administered by trained healthcare professionals in a clinical setting, eye drops can be administered by the patient themselves anywhere, resulting in large healthcare cost savings.
Worldwide, there were 14 million intravitreal injections performed in 2018 and it’s a number that has been growing 20% year-on-year. The drivers of treatment are the ageing global population and metabolic disease such as diabetes. About one third of people living with diabetes will suffer from diabetic retinopathy. Age-related macular degeneration (AMD) is also a leading cause of vision loss in Europe and the US. Currently, 196 million people are estimated to be affected by AMD globally, a figure expected to hit 288 million by 2040.
In the next 12 to 18 months, Naa Dei anticipates applying for InnovateUK Grant funding and looks forward to completing pre-clinical trials and having a dossier for approval for clinical trials.
2020 – Awarded a Royal Academy of Engineering’s Enterprise Fellowship.
2020 – Piloting trials of technology with a pharmaceutical company.
“[The Enterprise Fellowship] has opened my eyes to what goes into turning a neat idea into a business and has equipped me with tools to do so. It’s an amazing network of people at different stages of their enterprises, and I’ve found it very supportive.”
Sustainable construction demands better management of social and environmental impact. To achieve this, reliable, efficient tools are needed to make sense of large volumes of data across the range of related fields.
Qflow is a cloud-based platform that enables construction projects to manage their environmental risk and stay compliant with environmental standards.
Qflow brings together machine learning and the Internet of things to capture and analyse environmental data, making it easier to identify and manage risk. This increases productivity and reduces cost while positively impacting the built environment.
The technology connects to existing, on-site systems to automate real-time data collection and analysis. This leads to better informed decisions, more accurate predictions and the ability to generate standardised reports. It reduces costs associated with delays and mitigation processes caused by unmanaged environmental risk.
Trials have shown that Qualis Flows’ solutions can improve data capture against existing competitors by over 100%. Four pilot programmes are scheduled for spring 2019 to further validate the technology’s use in monitoring aspects such as waste, noise, air quality and vibration.
Brittany Harris brings significant experience in civil engineering as she leads a multi-skilled team of engineers, environmental professionals and software architects as Qualis Flow brings its solutions to market.
The array of switches, buttons, wheels and controls that help us to interact with electronics all rely on bulky and complex networks of sensors that can cost a lot to create.
TG0 has developed a new technology for making interactive 3D controls that are ergonomic, intuitive and engaging. Its solutions replace complicated networks of electronic sensors with one uniform, flexible, touch-sensitive material.
Driven by artificial intelligence algorithms and advanced signal processing, TG0’s platform technology can accurately detect variations in touch across a single flexible surface. This allows its material to easily sense pressure, location, speed, direction and movement allowing users to engage in more intuitive ways.
As Co-Founder, Ming leads research and development for the technology’s hardware. TG0’s seamless, interactive surfaces can be used in a range of applications including tactile gaming controls, car dashboard controls and ergonomic computer peripherals such as keyboards, amongst many others.
TG0 is also exploring how its technology can be used to make interactive products that are more accessible for the visually impaired.
Since its launch in 2016, TG0 has worked with high profile brands and manufacturers in the consumer and automotive sector and built a patent portfolio with more than ten international patent entries to date. A rapidly growing team is helping the company to expand and target a range of industries including sensor-embedded industrial robots, wearables, gadgets and underwater electronics.
"Getting to grips with a whole new mechanism for sensing and control doesn’t come naturally when you’ve spent your life learning to use another system."
The flexible and printed electronics markets are working towards having speedy, defect-free manufacturing processes. To achieve this, they need new inspection systems that allow live testing and enable real-time quality assurance without stopping production.
Dr Muhamedsalih has helped create a multi-wavelength polarising interferometer (MPI) for in-line surface metrology. It operates at the micro/nano-scale level and can be used for real time inspections of moving surfaces. The interferometer is combined with a software method to handle larger amount of data for surface analysis without direct interaction from the operator.
The system detects and characterises defects. This means that manufacturers will be able to understand what causes faults and take measures to correct them. Importantly, the technology is sufficiently robust to be used on the shop floor.
Hussam is now working to validate the MPI’s performance with world-leading manufacturers and research centres. His innovation is being tested by the UK Catapult National Centre for Printable Electronics – Centre for Process Innovation. His proof of concept system should reach Technology Readiness Level 9 before the end of 2021 and be ready to launch and available to buy soon after.
Analysts have forecast that the global metrology market will grow to over $600 million by 2023 in the traditional manufacturing market. Hussam’s technology also fits into the printed and flexible electronics markets, which are predicted to grow to $77 billion by 2023.
For Dr Muhamedsalih, the Enterprise Fellowship experience has: “allowed me to structure my business model and test it out by intensive direct interaction with industry and potential clients.”
Women deserve a better way of getting professionally fitted for bras. The lack of care and proper training within the bra industry means that bra-sizing confusion is a never-ending debate. Inefficient practices result in 80% of women wearing bras that don’t fit properly and billions of pounds lost every year in size- and fit-related exchanges and returns.
Combining state-of-the-art computer vision with data from real-life women (our co-creators), Brarista is bringing professional bra-fitting to bra-wearers’ homes. Its technology makes it possible for clients to find their best fit across product lines simply by using their phone camera.
Researching this technology to ensure its usefulness and accuracy is technically complex. Brarista is working hard to continue building, testing, and improving the current prototype before conducting technical trials.
The ongoing pandemic gave Brarista an opportunity to collaborate with Boost Innovations Ltd to apply its technology to fit breast prostheses online for breast cancer survivors (classified by the NHS as a higher-risk group). Research shows that getting bra-fitted using a tape-measure results in a 70% inaccuracy rate, but this is still the most popular method used by high street bra-fitters and online bra-fitting guides. Brarista hopes that its technology will improve the accuracy by at least 40% to be on par with professional bra-fitting by eyesight.
2018 - Won the Most Innovative Idea at the UCL Innovation and Enterprise Launch Programme
2019 - Team formation and acquired trial interests from the industry
2019 - Selected as a startup to be mentored by DeFine Network EU (a European Commission-funded FashionTech Community).
2019 - Selected as one of seven startups to join Women in AI & Data in Israel with InnovateUK
2019 - Highly Commended Award at the Academy’s Enterprise Hub Launchpad Competition Final
2020 - Crowdfunded successfully and matchfunded with NatWest Back Her Business
2020 - Acquired a new research client to apply its technology to fit breast prosthesis online
To find out more abut Brarista visit https://www.brarista.co/
“[The programme has helped by] providing the network of supporters, coaches and mentors that help me grow as an entrepreneur.”
For decades, satellites have been getting smaller but the rockets that launch them haven’t. Most active vehicles are still designed for historically large satellites and this is forcing a new generation of SmallSats to rideshare on enormous rockets in an expensive system of compromise.
Of the small satellites forecast to be launched between 2021 and 2030, 70% are predicted to fall in the under 250-kilogram weight class. However, launch vehicles that can operate at this weight lack appropriate propulsion systems. There is a clear market demand for dedicated launch vehicles that can take small satellites exactly where and when they need to go, but the fundamental technical challenge is that rocket engines and their associated pumps and turbomachinery are incredibly difficult to scale down. Attempts to scale down existing technology commonly result in spiralling costs and complexities.
Protolaunch believes that the right engine is the key to unlocking a successful microlauncher, and aims to supply that propulsion. It is developing an engine based around a novel thermodynamic cycle designed specifically for small payloads from the outset. This is possible because of its core engine technology, which acts as the enabler for a new type of launch vehicle.
The Protolaunch engine has three key advantages:
“Over the next 12 to 18 months, we look forward to working with the Royal Academy of Engineering as we build our long-term commercial strategy and start to engage with larger aerospace partners and customers.”
Better intraoperative guidance can help reduce patient morbidity and healthcare costs across surgical specialties. For example, brain tumour patients undergoing surgery have significantly improved outcomes and increased life expectancy if complete tumour removal is achieved. However, maximal resection needs to be balanced with the goal of healthy tissue preservation in order to minimise patient risk and neurological impairment. Yet, even with the most advanced current techniques, intraoperative decisions with potentially life-changing consequences are still based on the surgeon’s subjective visual assessment.
Hypervision Surgical has designed an AI-powered imaging system for wide-field tissue characterisation that attaches to and enhances existing surgical equipment. For the first time, surgeons will have real-time actionable information on tumour and critical brain structure margins during surgery. In addition, their system can monitor vital physiological tissue properties thereby increasing surgical precision and patient safety while optimising resection.
As a King’s College London spin-out, Hypervision Surgical is embedded in the St Thomas’ MedTech Hub and has close ties with King’s Health Partner hospitals. Further clinical studies are scheduled to develop and evaluate their technology to achieve commercial readiness.
Dr Ebner was awarded an Enterprise Fellowship award in 2020 to support him as he leads Hypervision Surgical in bringing its innovations to market.
Modern surgical implants use ‘press-fit’ and are hammered into place by the surgeon, creating friction that holds the implant in place. If the surgeon impacts the implant too rigorously, the bone may be over-stressed and fracture.
Bone fracture during hip replacement surgery affects between 2% and 8% of patients. If fracture occurs the patient is seven times more likely to need expensive revision surgery and twice as likely to die from complications.
Additive Instruments’ technology is a ‘smart’ surgical tool that can sense the force being applied to the instrument and adjust it to reduce the chances of fracture. By reducing the variation in impaction force, the technology also reduces the learning curve for new surgeons – reducing the likelihood of fracture through inexperience.
In the UK and US, 400,000 hip replacement procedures are conducted every year. If a conservative estimate of 2% of these surgeries were to result in fracture, 8,000 patients would suffer a painful and debilitating injury each year, most requiring revision surgery at great expense. These surgeries are estimated to cost £25 million every year.
Additive Instruments’ technology has been proven in the laboratory, so its next key milestone is to validate the product in a clinical environment, first with specimens and subsequently with live patients. Once the efficacy of the product has been proven, Additive Instruments will apply for a CE mark – a key achievement for any medical device.
Early laboratory development was supported by the Wellcome trust with a product translation award. Following the support of the Royal Academy of Engineering’s Enterprise Hub, Additive Instruments has been awarded an i4i (invention for innovation) award from the National Institute for Health Research (NIHR). This funding will help it achieve its goal of first clinical usage within the next two years.
“The real value of the Enterprise Fellowship is in the soft support I have received. Business coaching, workshops to develop interpersonal and planning skills, as well as brilliant insights from my mentor have all been hugely useful as Additive Instruments starts its journey into the commercial world.”
Commercial drones are now being used for several different roles such as mapping farms, inspecting buildings and search-and-rescue operations. Most commercial drone automation software on the market is generic, meaning drone operators and enterprises requiring customised solutions are forced to use many different types of software to get their job done. This becomes incredibly expensive and unreliable.
Hammer Flights Ltd is the world’s first adaptive flight automation software for unmanned aerial vehicles. It is highly versatile, supporting many different types of flight automation and yet is extremely simple to use. Using modular software architecture and APIs , the software morphs according to the task at hand.
Hammer aims to empower every drone operation in the world with adaptive flight automation to make their operations more productive, creative and safe. Its next key milestone is to understand how it can scale its enterprise offerings over the next 12 to 18 months.
The commercial drone industry is currently worth $13 billion and is expected to grow to $45 billion by 2025. A lot of this growth is attributed to enterprises rapidly setting up in-house drone teams and integrating drones into their existing workflows. Each one of these businesses will be looking for a customised flight automation solution that adapts to the needs of their business.
Hammer is currently grant funded by Ordnance Survey – the UK’s largest mapping agency – and the Royal Academy of Engineering through its Enterprise Fellowship programme. It has also formed strategic partnerships within the drone ecosystem.
“The Enterprise Fellowship has provided us with an amazing network of fellow entrepreneurs and mentors that we can learn from throughout our journey.”
What makes us different is the Academy’s Fellows and our wider Mentor network – an unrivalled community of the UK’s most successful industry leaders, technology experts and entrepreneurs. Find out more about our Mentors and their areas of expertise.
Professor Mark Arthur Tooley FREng is the immediate Past President of the Institute of Physics and Engineering in Medicine. He was the Head of the Department of Medical Physics and Bioengineering and Director of Research and Development at the Royal United Hospitals, Bath until 2017 when he retired from full-time NHS work. Since then, he has held several part-time roles. He is a specialist scientific advisor for NHS England, a digital clinical advisor for the West of England Academic Health Science network, and a healthcare technology consultant. He is a registered Consultant Clinical Scientist, an honorary professor at the University of Bath, and a visiting professor at the University of the West of England.
Mark completed his BSc in Electrical and Electronic Engineering at the University of Bath in 1979. He was sponsored by Westinghouse Brake and Signal company for the four years of the course. He then did an MSc and PhD in Medical Physics at the University of London. His MSc thesis was developing a EEG frequency analyser for anaesthesia. For his PhD research, Mark invented (with a cardiologist) an original method for rate-independent diagnosis of cardiac rhythm for implantable devices, which was patented. He spent the rest of his career in Medical Physics and Bioengineering departments, both in hospitals and academia, working along medical colleagues. He has worked at St Bartholomew’s hospital in London, Bristol University, United Bristol healthcare NHS Trust, and the Royal United Hospital, Bath. He is a Fellow of the Royal Academy of Engineering, the Royal College of Physicians, the Institute of Engineering and Technology, the Institute of Physics and Engineering in Medicine, and the Institute of Physics. He is a chartered engineer and chartered scientist. Mark is on the peer-review college of EPSRC, has recently been a member of the Engineering and Physical Sciences Research Council Healthcare Technologies Strategic Advisory Team and the Royal Society Fellowship panel.
Mark has been a long-standing member of the Panel for Biomedical Engineering at the Royal Academy of Engineering (now called the healthcare policy topic group). He was recently a member of the biomedical engineering membership panel, the Policy Committee, and the working group for Systems thinking in healthcare. He has mentored on the enterprise scheme.
Mark’s research interests include innovations in medicine, physics applications in anaesthesia, simulation in medicine, physiological measurement, biological signal processing, measuring the depth of anaesthesia, blood pressure measurement and novel patient monitoring solutions.
Brewster Barclay has been selling, marketing and product managing for more than 40 years in a wide variety of high technology industries including printed circuit boards, both manufacturing processes and capital equipment, 3D circuit boards, online advertising, optical sensors, military chip packaging, radar tubes and software engineering services. Brewster has worked at Zuhlke Engineering, e2v technologies, Clicktream Technologies, Orbotech and PCK Technology Kollmorgen.
The experience of launching new products and almost six years running an internet advertising startup led to Brewster giving back in the form of mentoring early stage and growth startups. He identified a massive gap in business development, sales support and strategy that angels, accelerators and VCs give to startups. He has focused solely on sharing his experiences in business development sales, sales techniques and the practicalities of day to day sales and lead generation.
He has mentored at the Royal Academy of Engineering for the past seven years as well as for Accelerate Cambridge, Seraphim Space Capital and many other groups.
Professor Anthony Dormer May OBE FREng has over 50 years' experience in transport planning and traffic engineering. He has been a professor at Leeds since 1977, and has served as Director of the Institute for Transport Studies, Head of the Department of Civil Engineering, Dean of the Faculty of Engineering and Pro-Vice Chancellor for Research. Between 1985 and 2001 he maintained a link between research and teaching at Leeds and practical experience in consultancy with MVA Ltd, where he was Director of Transport Policy.
Prior to 1977 he spent 10 years with the Greater London Council, where he was responsible for policy on highways, traffic management and transport-related land use planning for the capital. He managed major studies on traffic restraint, parking policy and motorway traffic control during his time there.
Anthony was elected a Fellow of the Royal Academy of Engineering in 1995, and awarded an OBE for services to transport engineering in 2004. He retired in 2009 but has remained active in research, consultancy and policy development. He served as President of the World Conference on Transport Research Society between 2007 and 2013. He has until recently been Editor-in-Chief of the European Transport Research Review and Secretary General of the World Conference on Transport Research Society. He currently chairs York Civic Trust's Transport Advisory Group, focusing on developing a sustainable transport policy for the city.
Mark joined Business Growth Fund in May 2011 and is based in London, with a UK wide role. He is part of senior management and assists the investment teams to assess the operational capability/opportunity of potential investees. He sits on the Board of a number of portfolio companies and works with many others where he is able to add value. He is also a member of the Industrial Development Advisory Board.
Mark has had 30 years’ experience in industry, primarily as the managing director/CEO of several manufacturing companies, including Pressurements Ltd, Druck Holdings Plc and General Electric, manufacturing a range of instrumentation and sensors covering sectors including aerospace, automotive, oil and gas, and test and metrology. He has also worked for M&H Plastic, a manufacturer of rigid plastic packaging for the personal care market. Mark has sold a number of the companies he has led and has successfully integrated bolt-on acquisitions.
Peter Childs FREng is the Professorial Lead in Engineering Design in the Dyson School of Design Engineering at Imperial College London and a Founder, Director and Chair of Q-Bot Ltd. His general interests include: creativity tools and innovation; design process and design rationale; fluid flow and heat transfer, particularly rotating flow; sustainable energy component, concept and system design; and robotics. He was the founding Head of School for the Dyson School of Design Engineering and prior roles include director of the Rolls-Royce supported University Technology Centre for Aero-Thermal Systems and director of InQbate at the University of Sussex.
He has contributed to over 200 papers, and several books including the Handbook on Mechanical Design Engineering as well as books on temperature and rotating flow. His roles at Imperial College London include Professor at Large for the Innovation Design Engineering double master’s degree run jointly by Imperial College London and the Royal College of Art and is Professor of Excellence at MD-H, Berlin. He is Editor of the Journal of Power and Energy.
Peter was elected a Fellow of the Royal Academy of Engineering in 2019.
Brian Palmer FREng is an entrepreneurial business leader in product design and manufacturing, who established Tharsus. The company focused on collaborative, complex, early-stage prototype development to help customers improve their products, before it evolved into an innovative business specialising in original equipment design and manufacture.
Today, he manages over 190 staff and has an impressive list of clients including BT, Ericsson, Fujitsu, Safety-Kleen, ITM Power, QinetiQ and Ocado. Brian Palmer has won two Cranfield Best Factory Awards and was named the Institute of Director’s North East Investor Director of the Year in 2013.
Philip Broad is an experienced finance director and business mentor working with companies across a range of sectors and growth stages. He holds an MEng (Hons) in electrical and mechanical engineering from the University of Edinburgh, and was a Royal Academy of Engineering Engineering Leadership Scholar Award holder while there.
He joined PricewaterhouseCoopers in London (audit) and subsequently spent two years based in the Transaction Services division in Frankfurt working with corporate and private equity investors in Germany. His experience since has included: commercial finance and corporate development roles in energy infrastructure; finance director of an energy infrastructure company in Denmark; interim finance director for divisions of a London-based FTSE 100 company; and startup experience.
Philip is a Fellow of the Institute of Chartered Accountants in England and Wales and an ICAEW Corporate Finance Faculty member.
Dr Andrew Muir has 30 years’ experience in growing and financing technology and high growth companies. He is a director of the Midven, a specialist fund manager where he manages the UK Innovation and Science Seed Fund (partnered with many of the leading UK publicly funded laboratories and their campuses) and the Stephenson fund (backed by the Institution of Mechanical Engineers).
After an initial scientific career at Zeneca, Andrew went on to roles in research and business development at the medical device company Biocompatibles and was then Vice-President of Technology for a US startup in disinfection of medical equipment.
He started his career in venture capital with the £4 million per annum Invention and Innovation seed capital fund at NESTA (the National Endowment for Science Technology and the Arts). He has a degree and a PhD in chemistry from the University of Oxford. Andrew is also currently on the investment committee for several funds managed by FSE, the iCure roundabout panel and the selection panel for the Royal Society of Edinburgh’s Enterprise Fellowship scheme.
Andrew combines a strong scientific and technical grounding with a real commercial pragmatism developed from his operational roles.
Iain is currently a non-executive director and Chairman of the Audit Committee of Premier Oil plc, a FTSE 250 global oil and gas company. He also serves as a Trustee Director and Chair of the Finance Committee for The Workforce Development trust Ltd. Until April 2020 he was also a non-executive director and Chairman of the Audit Committee at SUEK Ltd, Russia’s largest coal producer. Prior to his portfolio activities, Iain was Chief Financial Officer (CFO) of Fairfield Energy Ltd, a North Sea oil and gas company, where he oversaw all finance-related activities of the private equity backed organisation, including a potential IPO and a merger.
Iain also spent 30 years at BP, firstly as an engineer and project manager, where he was instrumental in developing technology licensing sales and projects in Asia. He then spent 10 years running various technology-led chemicals businesses, and the Prudhoe Bay oil field operations in Alaska, before being appointed a Group Vice President and holding roles as Head of Group Planning, Group Controller, and lastly Deputy Group CFO. He led the centralisation of the finance function of BP during this time, and its standardisation of processes and practices following the company’s significant merger and acquisition activity in the late 1990s.
Iain is a Fellow of the Institution of Chemical Engineers, a chartered engineer, and has an engineering degree from University College London. He also attended the Executive Education programme at Harvard Business School, and lives close to London, UK.