Current joint replacement systems use a standardised one-size-fits-all approach, despite the fact that bone shape and size can vary enormously.

Susannah had the idea to create fully-customised parts for surgery. She is a co-founder of Imperial College London spin-out Embody Orthopaedic that now make unique instruments designed specifically for a one person’s surgical intervention. 

Embody are pioneering low-cost instrumentation for orthopaedic surgery with a new type of 3D printed technology to revolutionise joint replacements. This approach decreases risk by creating instrumentation such as knee replacements that are unique to each patient. The minimally invasive devices are printed in nylon, a low-cost, robust material that can be readily sterilised.

Susannah’s instruments are now used in both everyday surgery and more specialised cases, such as soldiers with lower limb gunshot wounds. Using 3D printing technology enables a very complex operation to be planned and undertaken in a much reduced timeframe, allowing an entirely personalised surgical approach at an affordable cost.

Embody is expanding on 3D printing customisable implants. Furthering plans to deliver a fully tailored joint replacement process, from surgical planning to recovery, the company is also launching a web-based surgical planning system. This allows surgeons to upload patient scans and trial different surgical scenarios pre-operatively. Within the next ten years, Susannah plans to apply the technology in other fields such as maxillofacial, cardiovascular and dental surgery.

The problem

Balancing electrical supply with consumption is a challenge for power grids. An added difficulty is maintaining the balance across different timescales – from milliseconds to seasons. Sustainable grid management solutions need to manage intermittent supply from sources, including renewables. New technologies with long-term durability are needed to manage these demands.

The solution

Gyrotricity Ltd, a spin out from City, University of London, has developed a new technology for kinetic energy storage. . The technology is based on a flywheel, a steel rotor that stores energy that can be converted to electrical energy and released quickly on demand.

Gyrotricity’s flywheel is made using thin layers of laminated steel. As a result, it is more durable and safer than single-mass steel flywheels, as any potential damage can be easily contained. The company has also designed an electrical motor generator that lasts for up to 25 years, and is used for transmitting and retrieving power from the flywheel. Combined, the systems provide a lightweight and cost-effective solution to energy storage in the grid.

The Gyrotricity flywheel has two to four times greater energy density than conventional steel flywheels. High power, at the megawatt scale, can be provided by having flywheels connected in banks in containers. Gyrotricity is currently designing and testing these in the laboratory and at customer sites.

Professor Keith Pullen, Chief Technical Officer, holds the patents for the laminated flywheel technology. He draws on over twenty years of expertise in the field as he supports Gyrotricity in bringing its solutions to market.

Traction

• 2017:  Rail Safety and Standards Board funded development of the Gyrotricity flywheels in rail.
• 2018: Awarded funding from the Department for Business, Energy and Industrial Strategy Energy Entrepreneurs Fund.

Professor Pullen was awarded a 2018 Enterprise Fellowship to support him in refining Gyrotricity’s flywheel technology and bringing it to market.

The problem

Simulations can provide insights and analyses that transform and optimise businesses across sectors. Yet creating simulations is a highly specialised task that requires expensive software and hardware as well as expertise in network analysis, physics and software engineering. This means that many companies find it challenging to access.

The solution

Slingshot Simulations aims to make simulation and data analytics more accessible through its user-friendly simulation service. The automated, integrated cloud-based service is a fast, cost-effective route to accurate simulation.

Slingshot uses a patent-pending optimisation technique for automated analysis of big data. The technology is based on over a decade of research and development, in close collaboration with industry. It can quickly handle large amounts of data to create real-time simulations for use in forecasting and analysis.

Dr David McKee was closely involved in the development of the technology as the company’s Lead Technological Architect while at the University of Leeds. As CTO, David leads the company as it extends its scalable platform for companies in sectors including logistics, real estate, city planning, sustainable design and insurance.

The insights gained by more cost-effective, readily-accessible simulation services have been shown to improve clients’ market share by 2% to 3%. With such potential to influence business, Slingshot simulations is well placed to impact the global simulation market, currently valued at $6.5 billion.

Traction

• 2013 to 2018 – Funding awarded by the Engineering and Physical Sciences Research Council and Jaguar Land Rover for research and development.
• 2017 – Collaboration with IMC Business Architectures, Canada a leading company in artificial intelligence solutions.

Dr McKee was awarded a 2018 Enterprise Fellowship to further develop University of Leeds spin-out, Slingshot Simulations. 

The problem

Over 70% of the world’s coastlines experience erosion, which is increasing at an exponential rate due to climate change. Coral reefs provide valuable ecosystems that naturally prevent this erosion, but these are also rapidly being lost globally. 

The solution

Zyba Ltd has developed CCell, a technology that uses wave energy to create artificial coral reefs in any shape or size. This can provide a long-term, ecological solution to coastal erosion, restoring fisheries and enhancing tourism in the process by creating new scuba dive sites.

CCell technology is an ultra-lightweight energy converter that uses ocean waves to generate electricity. This is used to power BioRock – a process of electrolysis that makes sea minerals form around a steel structure, effectively creating a reef. The process enables corals to grow up to five times faster than they would naturally.

Many coastal regions such as those in Indonesia, the Dominican Republic and Mexico rely heavily on tourist income. Governments and the hotel industry absorb the high costs of coastal protection and many current solutions are both temporary and, in some cases, can increase erosion rates over time.

CCell has gained significant interest in Mexico where local partners have been supporting pilot projects to demonstrate the benefits in this key market. Future plans include scaling up the technology to increase access to a market that is valued at £16 billion globally. Tara Massoudi leads Business Development at Zyba Ltd and is responsible for developing the partnerships that will support the growth of the company and the implementation of its core technology, CCell.

Traction

• 2015: Innovate UK and Engineering and Physical Sciences Research Council award of £1.8 million to accelerate the development of CCell.
• 2018: First pilot unit installed in a test site in Mexico. 
• 2019: Zyba Ltd enters a collaboration with the National Commission of Natural Protected Areas Mexico to explore the potential impact of CCell and validate the technology. 

In 2018, Tara Massoudi was awarded an 1851 Royal Commission Enterprise Fellowship to support Zyba as it expands and brings its technology to market. Zyba Ltd has also been supported by Innovate UK as well as the EU Commission as part of a Horizon 2020 project.

The problem

During ‘last mile’ journeys, vaccines can be exposed to temperatures that are too high or too low, meaning they arrive damaged.

The World Health Organization estimates that between two to three million children die each year from vaccine-preventable disease. In 2018, 20 million children still lacked basic vaccinations. Current vaccine carriers last for hours whereas ‘last-mile’ journeys can take up to seven days. The wastage can be up to 85%, which increases when journeys exceed the current vaccine carrier’s capacity. 

The solution

Ideabatic’s solutions target the last-mile cold-chain issues with SMILE, a smart last-mile vaccine cooling system. It helps to preserve vaccines so that they remain effective in the last few miles of delivery and arrive safely.

Vaccines are often transported by foot, bike, canoe or donkey. ‘Last-mile’ journeys can last up to seven days with little infrastructure or electricity available to help preserve vaccines. SMILE has a last-mile capacity of three to five days without external power and can carry vaccines for over 500 people. Using the technology requires minimal training, supporting its aim to reduce vaccine wastage to below 5%.

The technology keeps vaccines within the right temperature range without an external power source. It uses a self-closing door that minimises human error and heat damage, and an extraction system that ensures that remaining vaccines are not exposed to excess heat when others are removed.

Kitty Liao has over ten years’ experience in multi-disciplinary system design and low-temperature research and development. She is leading Ideabatic as it conducts field trials in Africa and prepares for launch in 2020. The startup works with field experts and the Centre for Global Equality, and welcomes collaboration to accelerate the launch of SMILE. 

Traction

• 2019: Awarded the Expo 2020 Dubai Scale-up Grant from Expo Live, Expo 2020 Dubai.
• 2019: Awarded IP Audit Award from UK Intellectual Property.
• 2018: Awarded the Expo 2020 Dubai Innovation Impact Grant from Expo Live, Expo 2020 Dubai.
• 2017: Awarded the MassChallenge UK, Viiv Healthcare Startup Award.
• 2016: Awarded the First Prize in the Next Generation Healthcare Innovation Challenge from the Institute of Global Health.
• 2016: Awarded an IP award from Imperial Innovations.

Kitty Liao was awarded a 2018 Enterprise Fellowship to support her work in refining the technology, trialling its use and bringing it to market.

The problem

Large scale farming operations have well established methods for converting farm waste into renewable fuel and natural fertiliser. Small farms need access to scaled-down, efficient waste management solutions to make sustainable processes more widespread.

The solution

EcoNomad delivers small scale technology for sustainable resource management and agricultural waste reduction. Its sustainable, affordable technologies enable waste recycling and management, empowering smallholding farms and rural communities to be more self-sufficient.

EcoNomad’s range of solutions include a biogas and nutrient recovery system, known as the BioNomad™, that can be used on small farms to turn agricultural waste into biofuels for heating and an enriched liquid fertiliser. The technology was tested and demonstrated to add value during a four-year trial at a farm in London.

Another solution is EcoNomad’s patented technology for low-cost solar water pumping and pasteurisation, which works using passive thermal principles, without the need for electricity or moving parts.

Dr Ilan Adler identified a need for scaled down technologies during work in Mexico that resulted in him setting up a non-governmental organisation and co-founding a social enterprise to promote eco-technologies in rural communities. This inspired later research in the UK that led to the development of EcoNomad.

Following the success of its pilot, EcoNomad has further trials planned in the UK and Mexico, aiming to bring its first products to market in 2019.

Traction

• 2019: London Business School Launchpad programme awarded to spin-out.
• 2019: European Regional Development Fund grant awarded in collaboration with University College London (UCL) and Rothamsted Research (agricultural institution in the UK) for full-scale prototype testing.
• 2018: Support and mentoring provided by UCL Innovation and Enterprise. 
• 2018: Santander Research Catalyst Award granted for early-stage solar technology testing in collaboration with Centre for Scientific Research of the Yucatan Peninsula, Mexico.
• 2017: Biogas prototypes in Surrey Docks Farm awarded the UCL Provost’s Public Engagement Award.

Dr Adler was awarded a 2018 Enterprise Fellowship to support him in making sustainable solutions for agricultural resource and waste management more widely available to smallholdings in the UK and Europe.

The fourth industrial revolution is changing every element of enterprise. Companies that innovate throughout the value chain, such as Tesla or Dollar Shave Club, are achieving breakthrough growth, 

While sales and marketing, product development, service and support and back office functions have seen significant digitisation and investment, manufacturing has been left behind. Often not integrated to the wider enterprise and with significant investments in legacy equipment, manufacturing has historically been a very hard environment in which to scale change. There is now a huge opportunity to drive digitisation and innovation in the supply chain to gain a competitive edge. 

George is founder of Make-Sense, which is building on five years of industrial Internet of Things experience in the LPG sector. Make-Sense provides a data collection and analytics platform that empowers the whole supply chain from the shop floor to the top floor to drive radical efficiency and growth improvements.

Make-Sense is working with several of the world’s largest consumer goods brands to radically transform how they can leverage manufacturing as a core part of their growth and efficiency strategies.

The problem

Wearable electronics are often rigid and limited in flexibility because of how they are manufactured. Wearable components often do not bend and stretch with the clothes that they are added to and can have issues with durability, especially when washed.

The solution

Textile Two Dimensional is a University of Cambridge spin-out that makes electronic inks using graphene, which can be printed directly onto textiles. These inks can be layered to create bespoke, functional and wearable electronics. The electronics, and graphene’s electrical and thermal conductivity properties, are integrated into the textiles while remaining flexible and washable. They can be comfortably worn and re-used several times, meaning that they are also cost-effective and environmentally friendly.

The company is working closely with end-product manufacturers to explore development for a range of smart wearables in areas such as personal health, fitness and wellbeing, protection and fashion.

Dr Tian Carey initially explored the potential for the technology during his PhD at the University of Cambridge’s EPSRC Centre for Doctoral Training in Graphene Technology. As a result, Textile Two Dimensional continues to work closely with the Cambridge Graphene Centre to promote innovative research with an emphasis on application.

Traction

• 2018: Textile Two Dimensional and Cambridge Enterprise collaborate to accelerate adoption to market.

Dr Carey was awarded a 2018 Enterprise Fellowship to support him as the team at Textile Two Dimensional grows and the company develops from an ink manufacturer to a wearable systems manufacturer.

CEO and Founder, Snap Vision

Building on a background in computer vision, Jenny Griffiths developed Snap Vision, a company offering visual search-based solutions for the fashion retail and publishing industry.

Snap Vision fuses visual search with fashion to improve the shopping experience. Its solutions turn any image into the start of a search, allowing its users to ‘shop the look’ in a magazine or the real world, and instantly learn more or discover similar alternatives.

The technology combines mathematical rulesets and deep learning algorithms to understand user preferences, including colour, shape and pattern, making it easier for consumers to find items that they want. This results in a better shopping experience and helps retailers to increase conversion rates, improve customer engagement and generate additional revenue.

Jenny, CEO and Founder, leads product development at Snap Vision while also setting a strategy for sales and fundraising. As an SME Leader since 2017, Jenny has benefited from training at the London Business School alongside mentoring support. This has helped her strengthen skills for leading a growing business.

Since receiving the award, Jenny has developed a number of strategic partnerships and successfully secured additional equity investment. This will support Jenny’s goal to rapidly scale the company’s sales cycle in its next phase of growth.

Dr Supti Sarkar leads the Technology and Investments Group at PwC. She is responsible for the commercialisation of new tech ventures across the firm, and works with in-house entrepreneurs to get their products market ready.

Supti was formally a management consultant at PA Consulting, where she worked with international and regional governments to support their trade and investment strategies. She was also part of Mayor Sadiq Khan's 2016 delegation to Chicago and New York as part of her role in supporting high growth companies entering the US market for the first time. Supti holds a first class degree and PhD in engineering from University College London and is mum to an eight-year-old daughter.

Dr Douglas C Anderson OBE FREng FRSE has a 40-year business career covering almost every aspect, at every level, of healthcare technology product design and product commercialisation processes.

Having trained in industrial design engineering (Edinburgh Napier University 1974), Douglas progressed from hands on designer to the management of design in the high-tech arena.

Using his consulting company Crombie Anderson as a base for innovation and incubation, he subsequently spun out three other high-tech startup companies, two of which became publicly traded business operating in medical fields.

Douglas was the prime mover in these businesses by leading both the innovation and commercialisation processes, including raising over £40 million in private and institutional funding prior to floatation. Today he is internationally recognised for his innovation and entrepreneurial experience and is a regular keynote speaker at healthcare and business congresses around the world.

In 1990, his five-year-old son Leif suffered a spontaneous retinal detachment that went undetected until it was too late to treat. Douglas was struck by the limited capability of diagnostic tools available to practitioners to examine the retina and decided to address this issue. He built a dedicated research team, which led to the formation of Optos plc, a business funded by Archangel from the outset.

Optos succeeded in designing and patenting a scanning laser ophthalmoscope: the world's first ophthalmic device that enabled eye care professionals to capture a digital ultra wide-field image of the almost the entire retina in a single scan. The new method of examining the retina, marketed as the optomap® Retinal Exam, is now offered as the preferred standard of care by tens of thousands of eye-care specialists globally. Over 200 million optomap® retinal exams have been conducted worldwide and a number of novel diagnostic techniques added to improve the understanding and treatment of a wider range of conditions that have been historically difficult to manage.

In 2006 Douglas was awarded an OBE for services to healthcare. Douglas was elected a Fellow of the Royal Academy of Engineering in 2013.

David is an investor and CEO with companies based on technology and innovation.  

After a degree in electrical engineering at the Technion and an MBA from INSEAD,  David worked his way to senior management and board level in a wide range of sectors including sustainability, construction, life sciences, manufacturing, mobile telephony, cyber security and software. His broad experience ranges from startups to public companies, from turnaround missions and crisis management to business development and growth.     

David is deeply involved in the UK startup space, as a member of UKBAA, VCs, EIS funds and university angel groups, and is an active mentor with the Royal Academy of Engineering and Imperial College London’s IVMS programme. He also serves as a non-executive on the board of directors of Kerur Holdings (a public company), the board of governors of the Technion, as an advisor with the US accelerator Silicon Catalyst and the board of trustees of Hadassah UK.

He believes that success comes from a culture of excellence, a multidisciplinary approach, and that the boundaries between B2B/B2C and startups/LargeCo are increasingly blurred.

Richard joined sustainability investment focused Earth Capital Group in 2009 and has worked both on the group’s investment in investment managers and direct growth company investments, including most recently the fund’s investments in SoftIron and Propelair. He takes a leading role in promoting technology transfer opportunities across the group’s international offices.

Prior to joining Earth Capital, Richard was an Investment Director with IBIS Asset Management Ltd, a London-based captive advisor to a large Caribbean conglomerate. Richard was earlier a senior manager in the London office of L.E.K. Consulting, a global strategy consultancy. During his five years with LEK he provided due diligence advice, in numerous large cap and mid-market private equity deals, and advised corporate clients on corporate strategy, business unit growth strategy, process redesign and cost reduction programmes.

A chartered engineer, his early career included successful engineering, operations and customer support management roles with Ford Motor Company and Visteon Corporation. Richard holds an MBA with Distinction from INSEAD and MEng and MA (First Class) degrees in engineering from the University of Cambridge. He is a chartered member of the Chartered Institute of Securities and Investment, and a Chartered Member of the Institute of Engineering and Technology and a Sainsbury Management Fellow.

Dr Andrew Hosty FREng is an international leader with over 15 years of non-executive board experience and 30 years of executive and management experience, spanning private equity, UK Plc and global blue-chip corporates. He is non-executive director of a companies including: RHI-Magnesita, the global leader in the manufacture and supply of refractories; James Cropper Plc, who create some of the world’s most distinctive and technically advanced paper products; and Rights and Issues Investment Trust Plc, a fund that focuses on small cap UK industrials. 

Andrew is Non-Executive Chairman of mOm Incubators ltd, a pre-revenue startup developing low-cost baby incubators for crisis zones. He is also Non-Executive Chairman of Nexeon ltd, a company developing next-generation cathode materials for lithium-ion batteries. From 2016 to 2018 Andrew was the CEO of the Sir Henry Royce Institute, the UK's home of advanced materials research and innovation. He was Chief Operating Officer of Morgan Advanced Materials, and served on the Plc Board as an Executive Director from 2010 to 2016. 

From 2013 to 2016 he served on the board of Consort Medical Plc, a healthcare company focused on developing advanced delivery technologies, formulation and manufacturing solutions for drugs. He is a Fellow of the Institute of Materials, holds a PhD from the Faculty of Engineering at the University of Sheffield and is a Fellow of the Royal Academy of Engineering (2011).

Chris McIntosh joined Methera Global as CEO in 2017. The company’s vision is to enable the delivery of digital applications to rural and underserved communities worldwide via a resilient constellation of Ka band MEO satellites. He previously spent seven years as CEO of ViaSat UK where he was responsible for the inception and growth of ViaSat’s UK satellite capabilities.  Headquartered in the US, ViaSat are renowned as being one of the most disruptive players in the satellite communications and security domain.

Before joining ViaSat Chris was CEO of Stonewood Group, developers of state-of-the-art cyber products and services.  He is a retired Lieutenant Colonel from the British Army and has worked within the challenging, high threat cyber and communications environment for over 30 years. He holds a BSc in computer science, MSc in design of computer systems and an MBA.  He is a member of the UKspace trade association and the National Security and Resilience Consortium, and is a chartered engineer. 

Roy Williamson has been helping companies see how their new innovations can disrupt markets for over 20 years.

For the past six years has been successfully helping early stage companies identify and define their strengths, enhance their uniqueness and develop their storylines to engage investors. Roy’s background is in engineering and cleantech and since 2013, he’s been supporting SMEs and entrepreneurs across a broad area of technologies and innovative business models.

Roy is an aeronautical engineer and started his career at Alstom, developing algorithms and models to estimate hardware costs of power generation gas turbines based purely on, often novel, thermodynamic cycles. He has assessed innovation ecosystems of the UK, published by the Organisation for Economic Co-operation and Development. He has also co-authored guides to support technology developers in the UK automotive sector assess technology readiness levels and help those in the biofuels sector to review pathways for second generation biofuels. He’s appraised novel technology solutions for blue-chip clients, developed proof of concepts and carried out due diligence activities to support investor decision making. He is passionate about the UK and knowledge-intensive companies, from software to deeptech.

Roy is Head of Origination at the Department for International Trade with relationships across the department’s teams, government and the UK’s innovation and investment ecosystem.

Professor Mark Arthur Tooley FREng is the immediate Past President of the Institute of Physics and Engineering in Medicine. He was the Head of the Department of Medical Physics and Bioengineering and Director of Research and Development at the Royal United Hospitals, Bath until 2017 when he retired from full-time NHS work.  Since then, he has held several part-time roles. He is a specialist scientific advisor for NHS England, a digital clinical advisor for the West of England Academic Health Science network, and a healthcare technology consultant. He is a registered Consultant Clinical Scientist, an honorary professor at the University of Bath, and a visiting professor at the University of the West of England.

Mark completed his BSc in Electrical and Electronic Engineering at the University of Bath in 1979. He was sponsored by Westinghouse Brake and Signal company for the four years of the course. He then did an MSc and PhD in Medical Physics at the University of London. His MSc thesis was developing a EEG frequency analyser for anaesthesia. For his PhD research, Mark invented (with a cardiologist) an original method for rate-independent diagnosis of cardiac rhythm for implantable devices, which was patented.  He spent the rest of his career in Medical Physics and Bioengineering departments, both in hospitals and academia, working along medical colleagues. He has worked at St Bartholomew’s hospital in London, Bristol University, United Bristol healthcare NHS Trust, and the Royal United Hospital, Bath. He is a Fellow of the Royal Academy of Engineering, the Royal College of Physicians, the Institute of Engineering and Technology, the Institute of Physics and Engineering in Medicine, and the Institute of Physics. He is a chartered engineer and chartered scientist. Mark is on the peer-review college of EPSRC, has recently been a member of the Engineering and Physical Sciences Research Council Healthcare Technologies Strategic Advisory Team and the Royal Society Fellowship panel.

Mark has been a long-standing member of the Panel for Biomedical Engineering at the Royal Academy of Engineering (now called the healthcare policy topic group). He was recently a member of the biomedical engineering membership panel, the Policy Committee, and the working group for Systems thinking in healthcare. He has mentored on the enterprise scheme.

Mark’s research interests include innovations in medicine, physics applications in anaesthesia, simulation in medicine, physiological measurement, biological signal processing, measuring the depth of anaesthesia, blood pressure measurement and novel patient monitoring solutions.

Dr Liane Smith FREng founded Intetech Ltd in 1991, winning the Queen’s Award for Innovation in 2012 for its software. She sold the business to Wood Group in 2013 and in 2018 she left to form a new consulting engineering business, Larkton Ltd.

Liane is enthusiastic about the capability of digital technologies to transform businesses, bringing efficiencies, cost reduction, production control and increasing safety. In her last role as Senior Vice President Digital Solutions for Wood, she built the new global service line and defined its strategy roadmap and development plan. Her expertise is in various specialist branches of engineering in the industrial and energy sectors and in software product design and commercialisation, data management, data analysis, and analytics.