We aim to foster a culture of entrepreneurship, innovation and success among engineers in the UK, creating economic growth and societal impact. At the heart of how we do this are the Hub Members, the promising entrepreneurs who we support through our programmes, and our Hub Mentors, the business leaders who volunteer their expertise and time to help the Hub Members succeed.
From manufacturing to medtech, our Hub Membership is made up of some of the UK’s most innovative entrepreneurs. But don’t just take our word for it: read more about our Hub Members to see how they are, without exaggeration, changing the world.
Minimally invasive surgery offers significant benefits over conventional surgery. Smaller incisions lead to faster healing times and improved patient outcomes. However, these intricate procedures can be challenging to perform. Up to one in six surgeries still result in complications, many of which could be prevented by using better surgical planning tools.
Innersight’s 3D modelling technology can be used by surgeons to improve operative planning. It uses medical scans to create interactive, 3D models of a patient’s anatomy. Surgeons can then refine these models, using interactive artificial intelligence tools, to plan surgeries and visualise potential risks.
The technology uses deep learning algorithms to create accurate models that can be viewed on mobile devices, used in virtual reality or 3D printed. Innersight’s solutions are web-based, allowing surgeons to build and view models from any computer with an internet connection without installing specialised software.
Their retrospective clinical study has shown that the technology has helped surgeons adapt their approach in up to one in five cases. This leads to better informed decisions about, for example, which vessels to clamp or the right area for tissue incision. By reducing the risk of complications, the technology will help patients to have shorter hospital stays and save healthcare providers money.
Dr Eoin Hyde, CEO, draws on significant experience in computational physiology and the development of medical devices, as he leads Innersight towards making its technology widely available.
From abdominal and thoracic soft-tissue operations to orthopaedics and cardiac surgeries, Innersight is expanding its products to capture a share of the global minimally invasive surgery market, currently valued at $40 billion.
Dr Hyde was awarded a 2018 Enterprise Fellowship to support him as he leads Innersight in bringing its solutions to market.
Wood biomass is a clean alternative to unsustainable petrol-derived materials, fuels and chemicals, but its use is limited as it requires fractionation, a complex and costly separation process.
Lixea, an Imperial College London spinout, has developed a sustainable, cost-effective method for biomass fractionation - the process for separating wood components for use in other materials.
Lixea’s technology makes uses of low-cost ionic liquids to separate wood components. Known as BioFlex, the technology serves as a one-size-fits-all process for use with different types of biomass including waste wood, agricultural by-products and sustainably grown energy crops.
Over 1.6 billion tonnes of waste woody biomass are available globally in forms such as waste wood, palm residues and wheat and rice straw. This is a significant market that could make use of Lixea’s solutions to turn wood biomass into components, cellulose and lignin. These can then be used to make products including papers and films, bio-plastics and fine chemical and bio-derived adhesives.
Named as one of Europe’s most promising game-changers under 30 by Forbes, Dr Florence Gschwend has continuously engaged in entrepreneurial initiatives both during her PhD and since. Her interest in using engineering for societal and environmental benefit inspired the development of Lixea. Florence now leads the spinout in designing a pilot facility to refine its technology.
Dr Gschwend was awarded a 2018 Enterprise Fellowship to support her work in developing the BioFlex technology and the growth of Lixea as it prepares to bring its solutions to market.
The construction industry sends millions of tonnes of waste to landfill each year, at significant cost to the industry and the environment. And new legislation requires that by 2025 at least 70% of all waste must be recycled.
These two factors are driving the construction industry to find alternative building methods and materials that reduce waste.
With help from the Innovation Fund of Zero-Waste Scotland, Sam founded the clean tech spin-out company Kenoteq to address this need.
Kenoteq has developed a patent-pending process using traditional earth-construction methods to make unfired bricks that do not use cement which have 90% of their content recycled from building and construction waste. Its unique production process and materials are classified as recyclable by the Scottish Environment Protection Agency.
As the new brick does not use gas firing, large manufacturers can eliminate the cost of gas-fired production and avoid additional carbon taxes under the EU Emissions Trading Scheme (EU ETS). The bricks offer a high thermal mass and are ‘breathable bricks’, reducing the need for air conditioning and air quality controls inside buildings by providing relative humidity buffering.
Flexible, transparent electronics are increasingly in demand to support advances in electronic technologies. However, developments in materials science currently limits the availability of materials with the right properties.
Graphexe Nanotechnology have used graphene to create an ultra-thin, flexible and transparent material known as GraphExeter. The material has a distinctive combination of properties – it is as conductive as metal and as flexible as plastics. This creates new possibilities for advances in electronics in areas such as flexible lighting, foldable screens and other display technologies.
As a researcher with expertise in two-dimensional materials, Dr Liping Lu is helping Graphexe Nanotechnology to design integrated manufacturing processes for consistent and reliable production. The aim is to draw on the material’s properties to make it in a cost-effective and environmentally sustainable way.
Graphexe Nanotechnology is working in partnership with leading technology companies to refine and develop the use of its material in a range of new devices. This includes collaborations with Cambridge Display Technology, a leading developer of flexible lighting, and BOE, a global leader in manufacturing displays for mobile phones, tablets, televisions and other consumer electronics.
As Graphexe Nanotechnology grows in scale, with support from its partners its focus is to target the display technology and OLED-based lighting industry, which has a projected value of $10 billion by 2028.
Dr Lu was awarded a 2018 Enterprise Fellowship to further develop Graphexe Nanotechnology.
Current joint replacement systems use a standardised one-size-fits-all approach, despite the fact that bone shape and size can vary enormously.
Susannah had the idea to create fully-customised parts for surgery. She is a co-founder of Imperial College London spin-out Embody Orthopaedic that now make unique instruments designed specifically for a one person’s surgical intervention.
Embody are pioneering low-cost instrumentation for orthopaedic surgery with a new type of 3D printed technology to revolutionise joint replacements. This approach decreases risk by creating instrumentation such as knee replacements that are unique to each patient. The minimally invasive devices are printed in nylon, a low-cost, robust material that can be readily sterilised.
instruments are now used in both everyday surgery and more
specialised cases, such as soldiers with lower
limb gunshot wounds. Using 3D printing technology enables a very
complex operation to be planned and undertaken in a much
reduced timeframe, allowing an entirely personalised surgical
approach at an affordable cost.
is expanding on 3D printing customisable implants. Furthering plans to
deliver a fully tailored joint replacement process, from surgical
planning to recovery, the company is also launching a web-based
surgical planning system. This allows surgeons to upload patient
scans and trial different surgical scenarios pre-operatively. Within
the next ten years, Susannah plans to apply the technology in other
fields such as maxillofacial, cardiovascular and dental surgery.
“The Enterprise Hub has given me access to opportunities that have played a big role in my progress, particularly being able to take time out from my research to focus on the project, and receiving business training. The events organised by The Enterprise Hub have also enabled me to meet some very experienced people in the industry who gave me their views on my project from a completely different perspective, which was invaluable.”
Balancing electrical supply with consumption is a challenge for power grids. An added difficulty is maintaining the balance across different timescales – from milliseconds to seasons. Sustainable grid management solutions need to manage intermittent supply from sources, including renewables. New technologies with long-term durability are needed to manage these demands.
Gyrotricity Ltd, a spin out from City, University of London, has developed a new technology for kinetic energy storage. . The technology is based on a flywheel, a steel rotor that stores energy that can be converted to electrical energy and released quickly on demand.
Gyrotricity’s flywheel is made using thin layers of laminated steel. As a result, it is more durable and safer than single-mass steel flywheels, as any potential damage can be easily contained. The company has also designed an electrical motor generator that lasts for up to 25 years, and is used for transmitting and retrieving power from the flywheel. Combined, the systems provide a lightweight and cost-effective solution to energy storage in the grid.
The Gyrotricity flywheel has two to four times greater energy density than conventional steel flywheels. High power, at the megawatt scale, can be provided by having flywheels connected in banks in containers. Gyrotricity is currently designing and testing these in the laboratory and at customer sites.
Professor Keith Pullen, Chief Technical Officer,
holds the patents for the laminated flywheel technology. He draws on over
twenty years of expertise in the field as he supports Gyrotricity in bringing
its solutions to market.
Professor Pullen was awarded a 2018 Enterprise Fellowship to support him in refining Gyrotricity’s flywheel technology and bringing it to market.
Simulations can provide insights and analyses that transform and optimise businesses across sectors. Yet creating simulations is a highly specialised task that requires expensive software and hardware as well as expertise in network analysis, physics and software engineering. This means that many companies find it challenging to access.
Slingshot Simulations aims to make simulation and data analytics more accessible through its user-friendly simulation service. The automated, integrated cloud-based service is a fast, cost-effective route to accurate simulation.
Slingshot uses a patent-pending optimisation technique for automated analysis of big data. The technology is based on over a decade of research and development, in close collaboration with industry. It can quickly handle large amounts of data to create real-time simulations for use in forecasting and analysis.
Dr David McKee was closely involved in the development of the technology as the company’s Lead Technological Architect while at the University of Leeds. As CTO, David leads the company as it extends its scalable platform for companies in sectors including logistics, real estate, city planning, sustainable design and insurance.
The insights gained by more cost-effective, readily-accessible simulation services have been shown to improve clients’ market share by 2% to 3%. With such potential to influence business, Slingshot simulations is well placed to impact the global simulation market, currently valued at $6.5 billion.
Dr McKee was awarded a 2018 Enterprise Fellowship to further develop University of Leeds spin-out, Slingshot Simulations.
Over 70% of the world’s coastlines experience erosion, which is increasing at an exponential rate due to climate change. Coral reefs provide valuable ecosystems that naturally prevent this erosion, but these are also rapidly being lost globally.
Zyba Ltd has developed CCell, a technology that uses wave energy to create artificial coral reefs in any shape or size. This can provide a long-term, ecological solution to coastal erosion, restoring fisheries and enhancing tourism in the process by creating new scuba dive sites.
CCell technology is an ultra-lightweight energy converter that uses ocean waves to generate electricity. This is used to power BioRock – a process of electrolysis that makes sea minerals form around a steel structure, effectively creating a reef. The process enables corals to grow up to five times faster than they would naturally.
Many coastal regions such as those in Indonesia, the Dominican Republic and Mexico rely heavily on tourist income. Governments and the hotel industry absorb the high costs of coastal protection and many current solutions are both temporary and, in some cases, can increase erosion rates over time.
CCell has gained significant interest in Mexico where local partners have been supporting pilot projects to demonstrate the benefits in this key market. Future plans include scaling up the technology to increase access to a market that is valued at £16 billion globally. Tara Massoudi leads Business Development at Zyba Ltd and is responsible for developing the partnerships that will support the growth of the company and the implementation of its core technology, CCell.
In 2018, Tara Massoudi was awarded an 1851 Royal Commission Enterprise Fellowship to support Zyba as it expands and brings its technology to market. Zyba Ltd has also been supported by Innovate UK as well as the EU Commission as part of a Horizon 2020 project.
During ‘last mile’ journeys, vaccines can be exposed to temperatures that are too high or too low, meaning they arrive damaged.
The World Health Organization estimates that between two to three million children die each year from vaccine-preventable disease. In 2018, 20 million children still lacked basic vaccinations. Current vaccine carriers last for hours whereas ‘last-mile’ journeys can take up to seven days. The wastage can be up to 85%, which increases when journeys exceed the current vaccine carrier’s capacity.
Ideabatic’s solutions target the last-mile cold-chain issues with SMILE, a smart last-mile vaccine cooling system. It helps to preserve vaccines so that they remain effective in the last few miles of delivery and arrive safely.
Vaccines are often transported by foot, bike, canoe or donkey. ‘Last-mile’ journeys can last up to seven days with little infrastructure or electricity available to help preserve vaccines. SMILE has a last-mile capacity of three to five days without external power and can carry vaccines for over 500 people. Using the technology requires minimal training, supporting its aim to reduce vaccine wastage to below 5%.
The technology keeps vaccines within the right temperature range without an external power source. It uses a self-closing door that minimises human error and heat damage, and an extraction system that ensures that remaining vaccines are not exposed to excess heat when others are removed.
Kitty Liao has over ten years’ experience in multi-disciplinary system design and low-temperature research and development. She is leading Ideabatic as it conducts field trials in Africa and prepares for launch in 2020. The startup works with field experts and the Centre for Global Equality, and welcomes collaboration to accelerate the launch of SMILE.
Kitty Liao was awarded a 2018 Enterprise Fellowship to support her work in refining the technology, trialling its use and bringing it to market.
What makes us different is the Academy’s Fellows and our wider Mentor network – an unrivalled community of the UK’s most successful industry leaders, technology experts and entrepreneurs. Find out more about our Mentors and their areas of expertise.
Former Inaugural Chair of the Enterprise Committee and a long-standing Academy Fellow, Ian Shott CBE FREng has played a prominent role in establishing the Enterprise Hub. His track record of helping businesses in the engineering and life science sectors transform their approach and improve their vision, ambition, business models and enterprise value is an invaluable resource.
Ian is the Founder and former Executive Chair of contract pharmaceutical development and manufacturing company ARCINOVA, which he sold to Quotient Sciences in February 2021 and continues as Senior Advisor to the board. Ian is also the Managing Director at investment and advisory firm Shott Trinova. Prior to his specialist investment work at Shott Trinova, Ian was the founder and CEO of Excelsyn, which was sold to an American multinational in 2010. Earlier in his career he held numerous senior executive positions at multinational life science companies across the globe.
Ian has a wealth of experience with major industry bodies. He is formerly the Chair of the UK government’s Leadership Forum for Industrial Biotechnology and a Governing Board Member of Innovate UK. Ian is also Visiting Professor at Oxford, Nottingham and Newcastle universities.
“Apart from a deep-seated passion to change the entrepreneurial landscape in the UK and rediscover our legacy from the industrial revolution, I am highly excited by the prospect of engaging with new young talent and using my experience to accelerate and amplify their success. I’ve been involved in mentoring for over a decade but believe the Hub offers a very special opportunity to work with the brightest and best”.
Andy’s career in industry has involved co-founding over a dozen spin-outs and start-ups, three of which floated on stock markets. Virata floated on NASDAQ and at its peak had a market capitalisation of $5 billion.
His most prominent successes have come through RealVNC, which won the prestigious MacRobert Award in 2013, and Ubisense plc. Collectively, these two organisations have received five Queen’s Awards for Enterprise.
In academia, Andy heads the University of Cambridge’s Computer Laboratory and is an Honorary Fellow of Trinity Hall and Corpus Christi College. Elsewhere, he served as President of the IET between 2012 and 2013, and in 2007 received a CBE for services to the computer industry.
Andy is co-founder and Chairman of pioneering remote access software developers RealVNC and is also Professor of Computer Technology at the University of Cambridge. He was elected a Fellow of the Royal Academy of Engineering in 1996.
“My own career experiences have demonstrated just how important it is that the bridges between academia and industry are present and robust, and also what can be achieved when the relationship works to its potential. The Enterprise Hub offers an invaluable opportunity for exceptional academics to work with experienced industry figures and bring truly exciting new technology businesses to fruition.”
Naeem Alvi is an award-winning brand strategist and the founder of Notepad. After years of helping fast-growth SMEs and big brands such as Nike, Adidas and RBS Natwest to better leverage their brand, Naeem founded Notepad to connect big brand experience with ambitious tech companies that want to define and scale up their brands effectively and affordably.
Recent achievements include:
John is Professor of Optoelectronic Systems and Dean of transnational Education at the University of Glasgow.
He moved to Glasgow in 1986, where he established an internationally leading research group addressing linear and nonlinear integrated optoelectronic systems. He developed new integration technologies for photonic integrated circuits based on quantum well devices and quantum well intermixing, which ultimately led to the formation of the spin-out company Intense Ltd in 2000.
Intense developed the world’s most advanced integrated laser systems, bringing monolithic laser arrays together with electronic ASICs and optics for precise energy delivery in a range of applications from printing to material processing. The monolithic laser arrays pushed reliability and manufacturing yields to new levels.
John has extensive experience of operating in both academic and high-technology industrial environments, and as a result has an excellent understanding of spinning out IP and creating commercial value from an academic base.
He has been involved with several start-up companies including Kelvin Nanotechnology Ltd (1997-2000); Compound Semiconductor Technologies Ltd (1999-2000) and Intense Ltd (now Intense Inc) (2000-2009).
John was elected a Fellow of the Royal Academy of Engineering (FREng) in 2007; Fellow of the Royal Society of Edinburgh (FRSE) in 2000; Fellow of IEEE (FIEEE) in 2000 ‘for contributions to development of integrated optics based on semiconductor quantum well devices’; and Fellow of the Optical Society (FOSA) in 2016 for ‘for contributions to quantum and photonics technologies and systems in III-V compound semiconductors’.
Alastair is Head of Analytics and Machine Learning at MDRxTECH, Mishcon de Reya's digital transformation consultancy.
Alastair is a UCL Computer Science PhD with a background in computer vision, analytics, machine learning, blockchain, strategy, and technology innovation. He is an experienced manager and entrepreneur who has built teams in both large and small organisations. He is regularly called upon to audit, evaluate and provide guidance to large scale technology programmes for MDRxTECH clients. An entrepreneurial and dynamic problem solver, Alastair co-founded Satalia, which builds and applies AI technology to solve efficiency problems for organisations such as Tesco and PwC. He also co-founded the venture backed WeArePopUp.com, and helped establish the IDEALondon innovation centre with Cisco Systems.
Alastair continues to maintain an active teaching role in the UCL School of Management (MSc Business Analytics) and Peking University, Beijing (MBA Technology Strategy). His research interests include technology strategy, blockchain, smart contracting and computational law.
Brewster Barclay has been selling, marketing and product managing for more than 40 years in a wide variety of high technology industries including printed circuit boards, both manufacturing processes and capital equipment, 3D circuit boards, online advertising, optical sensors, military chip packaging, radar tubes and software engineering services. Brewster has worked at Zuhlke Engineering, e2v technologies, Clicktream Technologies, Orbotech and PCK Technology Kollmorgen.
The experience of launching new products and almost six years running an internet advertising startup led to Brewster giving back in the form of mentoring early stage and growth startups. He identified a massive gap in business development, sales support and strategy that angels, accelerators and VCs give to startups. He has focused solely on sharing his experiences in business development sales, sales techniques and the practicalities of day to day sales and lead generation.
He has mentored at the Royal Academy of Engineering for the past seven years as well as for Accelerate Cambridge, Seraphim Space Capital and many other groups.
Vida is a behavioural change coach with over seven years’ experience helping people think differently and positively change lives. She helps people to build connection and balance in order to create a sustainable future for themselves, others and the world. Vida does this as a speaker, trainer and coach, focusing on wellbeing, self-care, belief change, and motivation.
Having worked in prisons and schools as well as the public sector with non-clinical NHS staff and private sector for companies such Telefónica and Wavin, she has a unique insight to share.
Professor Alison Noble is the Technikos Professor of Biomedical Engineering, in the Department of Engineering Science at the University of Oxford, and Associate Head of MPLS Division. She is a Fellow of the Royal Society (2017), the Royal Academy of Engineering (2008) and the President of the Medical Image Computing and Computer Assisted Interventions (MICCAI) Society, the international society in biomedical image analysis.
Alison’s research interests are in computer analysis of clinical and biological images and the development and translation into clinical practice of novel methodologies that provide new diagnostic and therapeutic image based biomarkers and software tools for image-based quantification and decision-making. Her research group works in close collaboration with clinicians and industry players. She is also a Founder and the Chief Technology Officer of a university spin-out company that is commercialising research from her laboratory (Intelligent Ultrasound Ltd).
She returned to Oxford as a University Lecturer in 1995 to set up a biomedical image analysis group. Biomedical image analysis has since grown to be the largest biomedical engineering activity in Oxford.
Alison has played a leading role in setting up the biomedical engineering undergraduate and postgraduate biomedical engineering teaching and training (MSc and CDT) programmes at Oxford over the last decade. She is a member of both the Oxford University’s Research and Education Committees (from Oct 2013), and has served or currently serves on a number of committees of the Royal Academy of Engineering and other national organisations as well as numerous research funding agency panels.
Bill is a leading scientist worldwide in the field of Medical Materials. His major research contributions have been recognised by numerous international awards, medals and memberships.
He has been the Professor of Medical Materials at the University of Cambridge; served as Director of Cambridge Pfizer Institute for Pharmaceutical Materials Science; Cambridge Director of CMI Interdisciplinary Research Cluster in Biomaterials and Tissue Engineering and Director of University of London Interdisciplinary Research Centre (IRC) in Biomedical Materials. He has been Head of Department, Dean, and Governor at Queen Mary University of London.
He has been the editor of the Journal of The Royal Society: Interface, the Journal of Materials Science: Materials in Medicine, the Journal of Materials Science, and of the Journal of Materials Science Letters.
Bill is Emeritus Professor of Medical Materials in the University of Cambridge. He is internationally recognised for his pioneering research contributions to biomaterials for medical devices, with awards including the Royal Academy of Engineering Prince Philip Gold Medal; the Royal Society Armourers and Brasiers Company Medal; the Kelvin Medal; the European Society for Biomaterials George Winter Award; the Japanese Society for Biomaterials Medal; the Institute of Materials Griffiths Medal and Chapman Medal; the UK Society for Biomaterials President's Prize; the Acta Metallurgica H.H. Holloman Award and the International Union for Physical Sciences and Engineering in Medicine Award of Merit.
Professor Bonfield's exceptional interdisciplinary contribution has been recognised by his election to all three UK National Academies as a Fellow of the Royal Society (FRS), a Fellow of the Royal Academy of Engineering (FREng) and a Fellow of the Academy of Medical Sciences (FMedSci).