Open surgery is the current standard for preparing patients for dialysis and bypassing blocked peripheral arteries. High failure rates (approximately 50%) in both cases present a serious danger to life and require repeat procedures, for US dialysis patients alone this adds up to $4.6 billion per year.
Sorin Popa, founder of Pathfinder Medical, developed an electronic catheter guidance system that enables clinicians to connect blood vessels in a minimally invasive way, eliminating the need for open surgery and improving outcomes for vascular procedures. This technology has the potential to reduce the cost and trauma associated with procedures to treat those with renal failure and peripheral arterial disease.
Worldwide 3.4 million patients have end stage kidney disease and require their blood to be routinely filtered externally through haemodialysis.
This requires surgery to open up the arm and prepare patients’ blood vessels by forming a connection between an artery and a vein (known as a fistula or vascular access site). Pathfinder Medical’s catheter system can be used to connect blood vessels using a small covered tube known as a ‘stent graft’.
This technology enables patients to receive kidney dialysis without surgery. It can also be used to bypass blocked vessels for those with peripheral arterial disease which affects over 200 million patients globally.
The technology improves outcomes for patients by reducing stress, discomfort and the risk of vascular access problems. It brings cost saving to healthcare providers by improving the efficiency of procedures and reducing the likelihood of costly repeat procedures.
The global market for the technology is worth over £3.8 billion annually. In the UK, the solution could save the NHS an estimated £45 million per annum on kidney dialysis alone.
A 2016 Enterprise Fellowship was awarded to Sorin to support the growth of his start-up as it trials its technology in preparation for commercialisation.