Conjugation Scientist - MediSieve

Location: London, UK
Closing date: 30 Sep 2020
Posted: 2 weeks, 3 days ago

Hours of Work: 37.5 hours per week (full-time)

Salary: £25-30k pa

To apply: Please send your CV and a cover letter explaining what you can bring to MediSieve to jobs@medisieve.co.uk.

The Company

MediSieve is an exciting medical device therapeutics start-up developing “magnetic blood filtration”, a revolutionary treatment for blood-borne diseases which removes pathogens directly from the bloodstream. Our technology is like dialysis, circulating a patient’s blood through an external loop to remove disease causing targets. While dialysis relies on non-specific size based filtration, MediSieve uses magnetic beads coated with antibodies to target specific components, and magnetic forces to extract them. Our initial target diseases are malaria, sepsis and leukaemia. More details on www.medisieve.com

Role

As a Conjugation Scientist you will be working alongside the Biochemistry team to develop our magnetic bead products. This is a hands-on lab position where you will be expected to assist in the development of new conjugation methods (eg literature search, drafting new protocols, etc), as well as performing conjugations on a regular basis under controlled SOPs. At the same time, you will be working on the formulation and stability studies of the bead products in the context of their clinical application. You will be expected to do the necessary data treatment and analysis, as well as producing experimental reports.

Essential Experience

  •        Relevant life sciences degree (eg Biochemistry, Chemistry)
  •        Bead/surface functionalisation with antibodies/proteins – good knowledge of conjugation methods (two years minimum)
  •        Hands-on experience in a biochemistry lab (two years minimum)

Desired Experience

  •        Antibody structure and stability
  •        Working under aseptic conditions
  •        Formulation (excipients, stability, shelf-life, etc)
  •        Magnetic bead knowledge/working experience
  •        Haematology/blood interaction with beads or devices.
  •       Development of IVD devices
  •        Working under an ISO13485 QMS

Attributes

  • Adaptable
  • Communicative
  • Proactive
  • Self-motivated

Benefits

  • 3% Company pension
  • 25 days holiday
  • Share options scheme
  • Free beer Thursdays and Fridays in the office

To apply: Please send your CV and a cover letter explaining what you can bring to MediSieve to jobs@medisieve.co.uk.

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